N-tert-butyl-2-(6-chloro-1-methyl-1H-indazol-3-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide

• 常用名: N-tert-butyl-2-(6-chloro-1-methyl-1H-indazol-3-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide
• 英文名: N-tert-butyl-2-(6-chloro-1-methyl-1H-indazol-3-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide
• CAS号: 1422772-08-4
• 分子量: 382.8
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₁₉ClN₆O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-tert-butyl-2-(6-chloro-1-methyl-1H-indazol-3-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide

物理化学性质

• 分子式: C₁₉H₁₉ClN₆O
• 分子量: 382.8
• InChIKey: GYZYQCKKUYZJRF-UHFFFAOYSA-N
• SMILES: Cn1nc(-c2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)c2ccc(Cl)cc21

靶点实验

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实验名称：Metabolic stability in human liver microsomes assessed as GSH adduct formation 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL2350543

实验名称：Efflux ratio of permeability in human Caco2 cells 来源：ChEMBL 靶标：Caco-2 External Id：CHEMBL2350849

实验名称：Aqueous solubility of the compound by lyophilisate solubility assay 来源：ChEMBL 靶标：N/A External Id：CHEMBL2350848

实验名称：Fraction unbound in human plasma 来源：ChEMBL 靶标：Plasma External Id：CHEMBL2350846

实验名称：Selectivity for human recombinant truncated SYK (360 to 365 amino acid residues) over... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2350853

实验名称：Selectivity for human recombinant truncated SYK (360 to 365 amino acid residues) over... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2350852

实验名称：Inhibition of SYK in human Ramos cells 来源：ChEMBL 靶标：Tyrosine-protein kinase SYK External Id：CHEMBL2350851

实验名称：Inhibition of SYK in human whole blood 来源：ChEMBL 靶标：Tyrosine-protein kinase SYK External Id：CHEMBL2350850

实验名称：Inhibition of human recombinant truncated SYK (360 to 365 amino acid residues) using ... 来源：ChEMBL 靶标：Tyrosine-protein kinase SYK External Id：CHEMBL2350855

实验名称：Selectivity for human recombinant truncated SYK (360 to 365 amino acid residues) over... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2350854

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