N-(5-((2-(2,2-Dimethylpyrrolidin-1-yl)ethyl)carbamoyl)-2-fluorophenyl)-7-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide

• 常用名: N-(5-((2-(2,2-Dimethylpyrrolidin-1-yl)ethyl)carbamoyl)-2-fluorophenyl)-7-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide
• 英文名: N-(5-((2-(2,2-Dimethylpyrrolidin-1-yl)ethyl)carbamoyl)-2-fluorophenyl)-7-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide
• CAS号: 1426531-23-8
• 分子量: 503.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₃₀FN₇O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-(5-((2-(2,2-Dimethylpyrrolidin-1-yl)ethyl)carbamoyl)-2-fluorophenyl)-7-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide

物理化学性质

• 分子式: C₂₇H₃₀FN₇O₂
• 分子量: 503.6
• InChIKey: MIBCJEHHQRRSRL-UHFFFAOYSA-N
• SMILES: Cn1cc(-c2ccn3c(C(=O)Nc4cc(C(=O)NCCN5CCCC5(C)C)ccc4F)cnc3c2)cn1

靶点实验

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实验名称：In vivo receptor occupancy at PDGFR-beta kinase domain in rat lung at 0.1 mg/kg, it m... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3855050

实验名称：Transcellular permeability of the compound by PAMPA 来源：ChEMBL 靶标：N/A External Id：CHEMBL3855036

实验名称：Solubility of the compound using 10%PEG200/95%D5W by high-throughput assay 来源：ChEMBL 靶标：N/A External Id：CHEMBL3855042

实验名称：In vivo receptor occupancy at PDGFR-beta kinase domain in rat lung at 0.1 mg/kg, it m... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3855044

实验名称：Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in prob... 来源：ChEMBL 靶标：Platelet-derived growth factor receptor alpha External Id：CHEMBL3855037

实验名称：Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presen... 来源：ChEMBL 靶标：Platelet-derived growth factor receptor beta External Id：CHEMBL3855038

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