1-ethyl-3-[4-[(1R,9S)-6-[(3S)-3-methylmorpholin-4-yl]-12-(oxetan-3-yl)-3,5,12-triazatricyclo[7.2.1.02,7]dodeca-2(7),3,5-trien-4-yl]phenyl]urea

• 常用名: 1-ethyl-3-[4-[(1R,9S)-6-[(3S)-3-methylmorpholin-4-yl]-12-(oxetan-3-yl)-3,5,12-triazatricyclo[7.2.1.02,7]dodeca-2(7),3,5-trien-4-yl]phenyl]urea
• 英文名: 1-ethyl-3-[4-[(1R,9S)-6-[(3S)-3-methylmorpholin-4-yl]-12-(oxetan-3-yl)-3,5,12-triazatricyclo[7.2.1.02,7]dodeca-2(7),3,5-trien-4-yl]phenyl]urea
• CAS号: 1428902-71-9
• 分子量: 478.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₃₄N₆O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 1-ethyl-3-[4-[(1R,9S)-6-[(3S)-3-methylmorpholin-4-yl]-12-(oxetan-3-yl)-3,5,12-triazatricyclo[7.2.1.02,7]dodeca-2(7),3,5-trien-4-yl]phenyl]urea

物理化学性质

• 分子式: C₂₆H₃₄N₆O₃
• 分子量: 478.6
• InChIKey: NHJAMHLWORQRFH-XWFZLUIHSA-N
• SMILES: CCNC(=O)NC1=CC=C(C=C1)C2=NC3=C(C[C@@H]4CC[C@H]3N4C5COC5)C(=N2)N6CCOC[C@@H]6C

靶点实验

查看更多实验

实验名称：Time dependent inhibition of CYP2C9 (unknown origin) 来源：ChEMBL 靶标：Cytochrome P450 2C9 External Id：CHEMBL2341357

实验名称：Time dependent inhibition of CYP2C19 (unknown origin) 来源：ChEMBL 靶标：Cytochrome P450 2C19 External Id：CHEMBL2341356

实验名称：Plasma protein binding in human at 5 uM after 4 hrs by rapid equilibrium dialysis 来源：ChEMBL 靶标：Plasma External Id：CHEMBL2341363

实验名称：Plasma protein binding in mouse at 5 uM after 4 hrs by rapid equilibrium dialysis 来源：ChEMBL 靶标：Plasma External Id：CHEMBL2341362

实验名称：Half life in iv dosed dog 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL2340895

实验名称：Inhibition of mTORC1-mediated S6RP phosphorylation in human PC3 cells xenografted in ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2340894

实验名称：Inhibition of mTORC2-mediated AKT phosphorylation in human PC3 cells xenografted in N... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2340893

实验名称：Inhibition of PI3Kdelta (unknown origin) at 1 uM 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform External Id：CHEMBL2340892

实验名称：Time dependent inhibition of CYP1A2 (unknown origin) 来源：ChEMBL 靶标：Cytochrome P450 1A2 External Id：CHEMBL2341355

实验名称：Clearance in dog liver microsomes 来源：ChEMBL 靶标：Liver External Id：CHEMBL2341354

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