4-(4-thieno[2,3-d]pyrimidinylamino)-N-(4-((4-methyl-1-piperazinyl)methyl)phenyl)-1H-3-pyrazole carboxamide

• 常用名: 4-(4-thieno[2,3-d]pyrimidinylamino)-N-(4-((4-methyl-1-piperazinyl)methyl)phenyl)-1H-3-pyrazole carboxamide
• 英文名: 4-(4-thieno[2,3-d]pyrimidinylamino)-N-(4-((4-methyl-1-piperazinyl)methyl)phenyl)-1H-3-pyrazole carboxamide
• CAS号: 1429515-49-0
• 分子量: 448.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₂H₂₄N₈OS
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 4-(4-thieno[2,3-d]pyrimidinylamino)-N-(4-((4-methyl-1-piperazinyl)methyl)phenyl)-1H-3-pyrazole carboxamide

物理化学性质

• 分子式: C₂₂H₂₄N₈OS
• 分子量: 448.5
• InChIKey: UDVJBRYBBSVDDS-UHFFFAOYSA-N
• SMILES: CN1CCN(CC1)CC2=CC=C(C=C2)NC(=O)C3=C(C=NN3)NC4=C5C=CSC5=NC=N4

靶点实验

查看更多实验

实验名称：Inhibition of human FLT3 by Hotspot assay 来源：ChEMBL 靶标：Receptor-type tyrosine-protein kinase FLT3 External Id：CHEMBL4155885

实验名称：Inhibition of CDK2 (unknown origin) at 0.123 uM by Hotspot assay relative to control 来源：ChEMBL 靶标：Cyclin-dependent kinase 2 External Id：CHEMBL4155886

实验名称：Inhibition of CDK2 (unknown origin) by Hotspot assay 来源：ChEMBL 靶标：Cyclin-dependent kinase 2 External Id：CHEMBL4155881

实验名称：Inhibition of CDK6 (unknown origin) by Hotspot assay 来源：ChEMBL 靶标：Cyclin-dependent kinase 6 External Id：CHEMBL4155882

实验名称：Half life in human liver microsomes preincubated for 5 mins followed by NADPH additio... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4155892

实验名称：Intrinsic clearance in human liver microsomes preincubated for 5 mins followed by NAD... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4155893

实验名称：Drug uptake in human liver microsomes up to 60 mins by LC-MS/MS analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL4155894

实验名称：Inhibition of CDK6 (unknown origin) at 0.123 uM by Hotspot assay relative to control 来源：ChEMBL 靶标：Cyclin-dependent kinase 6 External Id：CHEMBL4155887

实验名称：Inhibition of human FLT3 at 0.123 uM by Hotspot assay relative to control 来源：ChEMBL 靶标：Receptor-type tyrosine-protein kinase FLT3 External Id：CHEMBL4155888

实验名称：Growth inhibition of human MV4-11 cells harboring FLT3-ITD after 72 hrs by Cell-Titer... 来源：ChEMBL 靶标：MV4-11 External Id：CHEMBL4155889

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