(1S,2S,3R,4R)-3-[(5-chloro-2-{[(7S)-1-methoxy-7-(morpholin-4-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino}pyrimidin-4-yl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide

• 常用名: (1S,2S,3R,4R)-3-[(5-chloro-2-{[(7S)-1-methoxy-7-(morpholin-4-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino}pyrimidin-4-yl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
• 英文名: (1S,2S,3R,4R)-3-[(5-chloro-2-{[(7S)-1-methoxy-7-(morpholin-4-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino}pyrimidin-4-yl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
• CAS号: 1431697-87-8
• 分子量: 539.1
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₈H₃₅ClN₆O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (1S,2S,3R,4R)-3-[(5-chloro-2-{[(7S)-1-methoxy-7-(morpholin-4-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino}pyrimidin-4-yl)amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide

物理化学性质

• 分子式: C₂₈H₃₅ClN₆O₃
• 分子量: 539.1
• InChIKey: LAJAFFLJAJMYLK-CVOKMOJFSA-N
• SMILES: COc1c(Nc2ncc(Cl)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc2c1CCC(N1CCOCC1)CC2

靶点实验

查看更多实验

实验名称：AUC (0 to 12 hrs) in rat 55 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2066440

实验名称：Inhibition of human Flt3 at 1 uM 来源：ChEMBL 靶标：Receptor-type tyrosine-protein kinase FLT3 External Id：CHEMBL2067607

实验名称：AUC (0 to 12 hrs) in rat 100 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2066441

实验名称：Inhibition of human Flt4 at 1 uM 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 3 External Id：CHEMBL2067608

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：AUC (0 to 12 hrs) in rat 10 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2066438

实验名称：Inhibition of human Fer at 1 uM 来源：ChEMBL 靶标：Tyrosine-protein kinase Fer External Id：CHEMBL2067605

实验名称：AUC (0 to 12 hrs) in rat 30 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2066439

实验名称：Inhibition of human Fes at 1 uM 来源：ChEMBL 靶标：Tyrosine-protein kinase Fes/Fps External Id：CHEMBL2067606

实验名称：Drug level in SCID mouse tumor xenografted with human KARPAS299 cells expressing NPM-... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2066444

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