WAY-267464

• 常用名: WAY-267464
• 英文名: WAY 267464 dihydrochloride
• CAS号: 1432043-31-6
• 分子量: 654.587
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₂H₃₇Cl₂N₇O₄
• 熔点: N/A
• 闪点: N/A

WAY-267464用途

WAY-267464(WAY267464)是一种有效的选择性非肽催产素受体激动剂,Ki为58.4 nM,选择性比V1a,V2,V1b受体高100倍；表现出类似于催产素(OT)的抗焦虑样特征,还显着逆转由体内MK-801或安非他明诱导的声惊吓反射的前脉冲抑制的破坏。

WAY-267464名称

• 英文名: 4-(3,5-Dihydroxybenzyl)-N-{2-methyl-4-[(1-methyl-4,10-dihydropyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]benzyl}-1-piperazinecarboxamide dihydrochloride

WAY-267464生物活性

• 描述: WAY-267464(WAY267464)是一种有效的选择性非肽催产素受体激动剂,Ki为58.4 nM,选择性比V1a,V2,V1b受体高100倍；表现出类似于催产素(OT)的抗焦虑样特征,还显着逆转由体内MK-801或安非他明诱导的声惊吓反射的前脉冲抑制的破坏。
• 参考文献: References 1. Ring RH, et al. Neuropharmacology. 2010 Jan;58(1):69-77. 2. Hicks C, et al. J Neuroendocrinol. 2012 Jul;24(7):1012-29. 3. Hicks C, et al. Br J Pharmacol. 2014 Jun;171(11):2868-87. 4. Hicks C, et al. Psychopharmacology (Berl). 2015 Aug;232(15):2659-67. View Related Products by Target Oxytocin Receptor (OXTR)

WAY-267464物理化学性质

• 分子式: C₃₂H₃₇Cl₂N₇O₄
• 分子量: 654.587
• 精确质量: 653.228394

WAY-267464英文别名

• 4-(3,5-Dihydroxybenzyl)-N-{2-methyl-4-[(1-methyl-4,10-dihydropyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]benzyl}-1-piperazinecarboxamide dihydrochloride
• 1-Piperazinecarboxamide, N-[[4-[(4,10-dihydro-1-methylpyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]-2-methylphenyl]methyl]-4-[(3,5-dihydroxyphenyl)methyl]-, hydrochloride (1:2)