罗库溴胺

• 常用名: 罗库溴胺
• 英文名: Rocuronium
• CAS号: 143558-00-3
• 分子量: 529.77
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₂H₅₃N₂O₄
• 熔点: N/A
• 闪点: N/A

罗库溴胺用途

Rocuronium是一种氨基甾体类非去极化的神经肌肉阻断剂或肌肉松弛剂。

罗库溴胺名称

• 中文名: 罗库溴胺
• 英文名: rocuronium

罗库溴胺生物活性

• 描述: Rocuronium (Org-9426) 是一种氨基甾体类非去极化的神经肌肉阻断剂或肌肉松弛剂。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Konishi J, Suzuki T, Kondo Y, Baba M, Ogawa S.Rocuronium and sugammadex used effectively for electroconvulsive therapy in a patient with Brugada syndrome.J ECT. 2012 Jun;28(2):e21-2.

  [2]. Zhang Y, Xiang Y, Liu J.Prevention of pain on injection of rocuronium: a comparison of lidocaine with different doses of parecoxib.J Clin Anesth. 2012 Jul 2.

  [3]. Suzuki T, Nameki K, Shimizu H, Shimizu Y, Nakamura R, Ogawa S.Efficacy of rocuronium and sugammadex in a patient with dermatomyositis.Br J Anaesth. 2012 Apr;108(4):703.

  [4]. Illodo Miramontes G, Doniz Campos M, Filgueira Garrido P, Vázquez Martínez A.Rocuronium used in rapid sequence intubation and reversal with sugammadex in a patient with myasthenia gravis.Rev Esp Anestesiol Reanim. 2011 Dec;58(10):626-7.

  [5]. García Sánchez JI, Martínez Hurtado ED, Tordecilla Echenique YY, Santa-Ursula TJ.Rocuronium used after sugammadex.Rev Esp Anestesiol Reanim. 2011 Dec;58(10):620-1.

罗库溴胺物理化学性质

• 分子式: C₃₂H₅₃N₂O₄
• 分子量: 529.77
• PSA: 59.00000
• LogP: 4.30420
• InChIKey: YXRDKMPIGHSVRX-OOJCLDBCSA-N
• SMILES: C=CC[N+]1(C2CC3C4CCC5CC(O)C(N6CCOCC6)CC5(C)C4CCC3(C)C2OC(C)=O)CCCC1
• 储存条件: 2-8℃

罗库溴胺靶点实验

查看更多实验

实验名称：Compound was evaluated for inhibition of rat Gabra1 in an in vitro assay with cellula... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit alpha-1 External Id：CHEMBL5291801

实验名称：Binding affinity towards rat Gabra1 in an in vitro assay with cellular components mea... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit alpha-1 External Id：CHEMBL5291798

实验名称：Binding affinity towards human ESR1 in an in vitro cell free assay (NIBR assay) measu... 来源：ChEMBL 靶标：Estrogen receptor External Id：CHEMBL5291791

实验名称：Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1315

实验名称：A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS979

实验名称：Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry 来源：NCGC 靶标：N/A External Id：TRND-SARS-CoV-2-cytotox-48hr

实验名称：Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry 来源：NCGC External Id：TRND-SARS-CoV-2-PP

实验名称：Agonist activity at N-terminal Flag-tagged human MRGPRX2 receptor expressed in tetrac... 来源：ChEMBL 靶标：Mas-related G-protein coupled receptor member X2 External Id：CHEMBL5665199

实验名称：Agonist activity at N-terminal Flag-tagged human MRGPRX2 receptor expressed in tetrac... 来源：ChEMBL 靶标：Mas-related G-protein coupled receptor member X2 External Id：CHEMBL5665200

实验名称：Increase the activity of the Burkholderia fixLJ 2-component system 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Burkholderia multivorans External Id：HMS1625

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罗库溴胺英文别名

• Esmeron
• BIDD:GT0360
• [(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3-hydroxy-10,13-dimethyl-2-morpholin-4-yl-16-(1-prop-2-enylpyrrolidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
• Zemuron
• HMS2090E03
• Rocuronium