CTX-0294885

• 常用名: CTX-0294885
• 英文名: CTX0294885
• CAS号: 1439934-41-4
• 分子量: 437.925
• 密度: 1.3±0.1 g/cm3
• 沸点: N/A
• 分子式: C₂₂H₂₄ClN₇O
• 熔点: N/A
• 闪点: N/A

CTX-0294885用途

CTX-0294885是一种新型二苯胺嘧啶化合物，体外对广泛激酶有抑制活性，继而被开发为琼脂糖凝胶激酶检测试剂。

CTX-0294885名称

• 中文名: 2-[[5-氯-2-[[4-(1-哌嗪基)苯基]氨基]-4-嘧啶基]氨基]-N-甲基苯甲酰胺
• 英文名: 2-((5-chloro-2-((4-(piperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide

CTX-0294885生物活性

• 描述: CTX-0294885是一种新型二苯胺嘧啶化合物,体外对广泛激酶有抑制活性,继而被开发为琼脂糖凝胶激酶检测试剂。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 其他
• 参考文献:

  [1]. Zhang L, et al. Characterization of the novel broad-spectrum kinase inhibitor CTx-0294885 as an affinity reagent for mass spectrometry-based kinome profiling. J Proteome Res. 2013 Jul 5;12(7):3104-16.

CTX-0294885物理化学性质

• 密度: 1.3±0.1 g/cm3
• 分子式: C₂₂H₂₄ClN₇O
• 分子量: 437.925
• 精确质量: 437.173096
• PSA: 94.21000
• LogP: 2.22
• InChIKey: FCLOIQHNUARDSR-UHFFFAOYSA-N
• SMILES: CNC(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCNCC3)cc2)ncc1Cl
• 外观性状: off white solid
• 折射率: 1.674
• 储存条件: -20℃

CTX-0294885靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Confirmatory Screen for Target Class Profiling of Small Molecule Inhibitors of Methyl... 来源：NCGC External Id：MTASE-f-cherrypicks

实验名称：Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltrans... 来源：NCGC External Id：MTASE-p

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A4437

实验名称：Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve... 来源：NCGC 靶标：N/A External Id：OBG420

实验名称：Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu... 来源：NCGC External Id：CYP2D6395

实验名称：Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu... 来源：NCGC External Id：CYP2C9536

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-2C

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-9B

实验名称：Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) drug resistant ... 来源：NCGC External Id：s-sky_synergy-MV-411_DR-CTG72-MIPE_NPC_NPACT_Kinase-p1

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CTX-0294885英文别名

• CTx-0294885
• CTX0294885
• 2-[(5-Chloro-2-{[4-(1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzamide