1-[4-[(5-methoxy-3-pyridinyl)oxy]-5-[(3R)-oxan-3-yl]-2-pyridinyl]-3-methylurea

• 常用名: 1-[4-[(5-methoxy-3-pyridinyl)oxy]-5-[(3R)-oxan-3-yl]-2-pyridinyl]-3-methylurea
• 英文名: 1-[4-[(5-methoxy-3-pyridinyl)oxy]-5-[(3R)-oxan-3-yl]-2-pyridinyl]-3-methylurea
• CAS号: 1442677-92-0
• 分子量: 358.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₂₂N₄O₄
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 1-[4-[(5-methoxy-3-pyridinyl)oxy]-5-[(3R)-oxan-3-yl]-2-pyridinyl]-3-methylurea

物理化学性质

• 分子式: C₁₈H₂₂N₄O₄
• 分子量: 358.4
• InChIKey: APSOPISMEDAYTH-LBPRGKRZSA-N
• SMILES: CNC(=O)NC1=NC=C(C(=C1)OC2=CN=CC(=C2)OC)[C@H]3CCCOC3

靶点实验

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实验名称：Antidiabetic activity in po dosed Sprague-Dawley rat assessed as decrease in blood gl... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4427360

实验名称：Antidiabetic activity in Sprague-Dawley rat assessed as decrease in blood glucose AUC... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4427361

实验名称：Clearance in rat at 0.5 mg/kg, iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL4427362

实验名称：Clearance in mouse at 1 mg/kg, iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL4427363

实验名称：Volume of distribution at steady state in rat at 0.5 mg/kg, iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL4427364

实验名称：Volume of distribution at steady state in mouse at 1 mg/kg, iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL4427365

实验名称：Activation of human recombinant glucokinase assessed as enzyme affinity for glucose u... 来源：ChEMBL 靶标：Hexokinase-4 External Id：CHEMBL4427350

实验名称：Activation of human recombinant glucokinase assessed as Vmax ratio using 0.16 to 80 m... 来源：ChEMBL 靶标：Hexokinase-4 External Id：CHEMBL4427351

实验名称：Fraction unbound in rat plasma 来源：ChEMBL 靶标：N/A External Id：CHEMBL4427353

实验名称：Fraction unbound in mouse plasma 来源：ChEMBL 靶标：N/A External Id：CHEMBL4427354

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