3-(6,8-Dimethylimidazo[1,2-a]pyrazin-2-yl)-7-(4-methylpiperazin-1-yl)-2h-chromen-2-one

• 常用名: 3-(6,8-Dimethylimidazo[1,2-a]pyrazin-2-yl)-7-(4-methylpiperazin-1-yl)-2h-chromen-2-one
• 英文名: 3-(6,8-Dimethylimidazo[1,2-a]pyrazin-2-yl)-7-(4-methylpiperazin-1-yl)-2h-chromen-2-one
• CAS号: 1446310-46-8
• 分子量: 389.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₂H₂₃N₅O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 3-(6,8-Dimethylimidazo[1,2-a]pyrazin-2-yl)-7-(4-methylpiperazin-1-yl)-2h-chromen-2-one

物理化学性质

• 分子式: C₂₂H₂₃N₅O₂
• 分子量: 389.4
• InChIKey: GGBMOXHXNCDOPL-UHFFFAOYSA-N
• SMILES: Cc1cn2cc(-c3cc4ccc(N5CCN(C)CC5)cc4oc3=O)nc2c(C)n1

靶点实验

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实验名称：AUC (0 to 6 hrs) in Sprague-Dawley rat at 10 mg/kg, po 来源：ChEMBL 靶标：N/A External Id：CHEMBL4478619

实验名称：Ratio of drug level in brain to plasma of Sprague-Dawley rat at 10 mg/kg, po measured... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4478620

实验名称：Inhibition of mRNA splicing of human SMN2 exon 7 transfected in HEK293H cells assesse... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4478610

实验名称：Inhibition of mRNA splicing of SMN2 exon 7 in GM03813 fibroblasts derived from SMA pa... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4478614

实验名称：Apparent permeability in human Caco2 cells 来源：ChEMBL 靶标：N/A External Id：CHEMBL4478616

实验名称：Efflux ratio of apparent permeability from basolateral to apical over apical to basol... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4478617

实验名称：Protein binding in human plasma 来源：ChEMBL 靶标：N/A External Id：CHEMBL4478618

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