1-(4-((5-Cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo(2,1-F)(1,2,4)triazin-2-yl)-N-(6-(18F)fluoro-3-pyridinyl)-2-methyl-L-prolinamide

• 常用名: 1-(4-((5-Cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo(2,1-F)(1,2,4)triazin-2-yl)-N-(6-(18F)fluoro-3-pyridinyl)-2-methyl-L-prolinamide
• 英文名: 1-(4-((5-Cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo(2,1-F)(1,2,4)triazin-2-yl)-N-(6-(18F)fluoro-3-pyridinyl)-2-methyl-L-prolinamide
• CAS号: 1446701-47-8
• 分子量: 460.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₄FN₉O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 1-(4-((5-Cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo(2,1-F)(1,2,4)triazin-2-yl)-N-(6-(18F)fluoro-3-pyridinyl)-2-methyl-L-prolinamide

物理化学性质

• 分子式: C₂₃H₂₄FN₉O
• 分子量: 460.5
• InChIKey: LQVXSNNAFNGRAH-SXBFPYQPSA-N
• SMILES: CC1(C(=O)Nc2ccc(F)nc2)CCCN1c1nc(Nc2cc(C3CC3)[nH]n2)c2cccn2n1

靶点实验

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实验名称：Binding affinity to IGF-1R in human grade 4 glioblastoma at 0.1 nM after 1 hr by phos... 来源：ChEMBL 靶标：Insulin-like growth factor 1 receptor External Id：CHEMBL2404067

实验名称：Binding affinity to IGF-1R in human breast tumor at 0.1 nM after 1 hr by phosphor ima... 来源：ChEMBL 靶标：Insulin-like growth factor 1 receptor External Id：CHEMBL2404066

实验名称：Binding affinity to IGF-1R in human pancreatic tumor at 0.1 nM after 1 hr by phosphor... 来源：ChEMBL 靶标：Insulin-like growth factor 1 receptor External Id：CHEMBL2404065

实验名称：Drug uptake in human grade 4 glioblastoma at 0.1 nM after 1 hr by phosphor imager aut... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2404064

实验名称：Drug uptake in human breast tumor at 0.1 nM after 1 hr by phosphor imager autoradiogr... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2404063

实验名称：Drug uptake in human pancreatic tumor at 0.1 nM after 1 hr by phosphor imager autorad... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2404062

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