8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide

• 常用名: 8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide
• 英文名: 8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide
• CAS号: 1449276-86-1
• 分子量: 322.3
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₁₅FN₄O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide

物理化学性质

• 分子式: C₁₈H₁₅FN₄O
• 分子量: 322.3
• InChIKey: XWLOYAAKIFUZDU-UHFFFAOYSA-N
• SMILES: Nc1ncc(C(=O)NC2CC2)c2ccc(-c3cccc(F)c3)nc12

靶点实验

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实验名称：Inhibition of MAP4K4 (unknown origin) by Z'LYTE assay 来源：ChEMBL 靶标：Mitogen-activated protein kinase kinase kinase kinase 4 External Id：CHEMBL3624922

实验名称：Apparent permeability in MDCK cells at 10 uM incubated over 60 mins 来源：ChEMBL 靶标：MDCK External Id：CHEMBL3624927

实验名称：Anti-angiogenesis activity in HUVEC assessed as inhibition of cell migration 来源：ChEMBL 靶标：HUVEC External Id：CHEMBL3624926

实验名称：Clearance in mouse liver microsomes assessed as compound remaining incubated for 1 hr... 来源：ChEMBL 靶标：Liver External Id：CHEMBL3624930

实验名称：Clearance in human liver microsomes assessed as compound remaining incubated for 1 hr... 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3624929

实验名称：Efflux ratio in MDCK cells at 10 uM incubated over 60 mins 来源：ChEMBL 靶标：MDCK External Id：CHEMBL3624928

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