2-(8-Fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-(4-methylpiperazin-1-yl)pyrido[1,2-a]pyrimidin-4-one

• 常用名: 2-(8-Fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-(4-methylpiperazin-1-yl)pyrido[1,2-a]pyrimidin-4-one
• 英文名: 2-(8-Fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-(4-methylpiperazin-1-yl)pyrido[1,2-a]pyrimidin-4-one
• CAS号: 1449592-94-2
• 分子量: 392.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₂₁FN₆O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-(8-Fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-(4-methylpiperazin-1-yl)pyrido[1,2-a]pyrimidin-4-one

物理化学性质

• 分子式: C₂₁H₂₁FN₆O
• 分子量: 392.4
• InChIKey: OCIABPGRNCLBEI-UHFFFAOYSA-N
• SMILES: CC1=CN2C=C(C=C(C2=N1)F)C3=CC(=O)N4C=C(C=CC4=N3)N5CCN(CC5)C

靶点实验

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实验名称：Fraction unbound in rat plasma 来源：ChEMBL 靶标：N/A External Id：CHEMBL4478571

实验名称：Fraction unbound in mouse plasma 来源：ChEMBL 靶标：N/A External Id：CHEMBL4478572

实验名称：AUC in plasma of C/C-allele mouse harboring FVB.129(B6)-Smn1tm5(Smn1/SMN2)Mrph/J at 1... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4478573

实验名称：Unbound AUC in plasma of C/C-allele mouse harboring FVB.129(B6)-Smn1tm5(Smn1/SMN2)Mrp... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4478574

实验名称：Inhibition of mRNA splicing of SMN2 exon 7 in C/C-allele mouse harboring FVB.129(B6) ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4478575

实验名称：Inhibition of mRNA splicing of SMN2 exon 7 in C/C-allele mouse harboring FVB.129(B6) ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4478576

实验名称：Inhibition of mRNA splicing of SMN2 exon 7 in C/C-allele mouse harboring FVB.129(B6) ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4478577

实验名称：Inhibition of mRNA splicing of SMN2 exon 7 in C/C-allele mouse harboring FVB.129(B6) ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4478578

实验名称：Half life in rat at 10 mg/kg, po 来源：ChEMBL 靶标：N/A External Id：CHEMBL4478563

实验名称：Oral bioavailability in rat at 10 mg/kg 来源：ChEMBL 靶标：N/A External Id：CHEMBL4478564

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