N-(2-aminoethyl)-2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide

• 常用名: N-(2-aminoethyl)-2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide
• 英文名: N-(2-aminoethyl)-2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide
• CAS号: 1463487-40-2
• 分子量: 391.27
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₅H₁₁F₆N₅O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-(2-aminoethyl)-2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine-8-carboxamide

物理化学性质

• 分子式: C₁₅H₁₁F₆N₅O
• 分子量: 391.27
• InChIKey: GJIYFZYSQJGEHK-UHFFFAOYSA-N
• SMILES: NCCNC(=O)c1cn2c(ccc3c(C(F)(F)F)cc(C(F)(F)F)nc32)n1

靶点实验

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实验名称：AUC ( 0 to infinity) in Wistar rat at 100 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3637696

实验名称：AUC ( 0 to 24 hrs) in Wistar rat at 100 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3637695

实验名称：Cytotoxicity against human Huh7.5.1 cells 来源：ChEMBL 靶标：N/A External Id：CHEMBL3637566

实验名称：Ratio of RO8191 EC50 to compound EC50 for HCV genotype 2a JFH-1 infected in human Huh... 来源：ChEMBL 靶标：Hepacivirus hominis External Id：CHEMBL3637565

实验名称：Antiviral activity against HCV genotype 2a JFH-1 infected in human Huh7.5.1 cells aft... 来源：ChEMBL 靶标：Hepacivirus hominis External Id：CHEMBL3637564

实验名称：Activation of ISRE reporter gene in human Huh7.5.1 cells at 2 to 50 uM after 24 hrs b... 来源：ChEMBL 靶标：Huh-7 External Id：CHEMBL3637570

实验名称：Activation of ISRE reporter gene in human HuH7 cells at 2 to 50 uM after 24 hrs by lu... 来源：ChEMBL 靶标：Huh-7 External Id：CHEMBL3637569

实验名称：Activation of ISRE reporter gene in African green monkey Vero cells at 4 to 100 uM af... 来源：ChEMBL 靶标：Vero External Id：CHEMBL3637568

实验名称：Antiviral activity against HCV genotype 1b Con-1 infected in human HuH7 cells after 7... 来源：ChEMBL 靶标：Hepacivirus hominis External Id：CHEMBL3637567

实验名称：Antiviral activity against HCV genotype 2a JFH-1 in human Huh7.5.1 cells assessed as ... 来源：ChEMBL 靶标：Hepacivirus hominis External Id：CHEMBL3637573

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