N-[2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基]-N-2-吡啶基环己烷甲酰胺盐酸盐

• 常用名: N-[2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基]-N-2-吡啶基环己烷甲酰胺盐酸盐
• 英文名: WAY 100635 Hydrochloride
• CAS号: 146714-97-8
• 分子量: 422.563
• 密度: 1.2±0.1 g/cm3
• 沸点: 594.8±50.0 °C at 760 mmHg
• 分子式: C₂₅H₃₄N₄O₂
• 熔点: 176-178°C
• 闪点: 313.5±30.1 °C

名称

• 中文名: N-[2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基]-N-2-吡啶基-环己烷羧胺三盐酸盐
• 英文名: N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-N-pyridin-2-ylcyclohexanecarboxamide,trihydrochloride

物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 594.8±50.0 °C at 760 mmHg
• 熔点: 176-178°C
• 分子式: C₂₅H₃₄N₄O₂
• 分子量: 422.563
• 闪点: 313.5±30.1 °C
• 精确质量: 422.268188
• PSA: 48.91000
• LogP: 2.66
• InChIKey: QDUDBLVWOSYWID-UHFFFAOYSA-N
• SMILES: COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1.Cl.Cl.Cl
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.590
• 储存条件: Refrigerator

靶点实验

查看更多实验

实验名称：Hypothermic effect in Swiss albino mouse assessed as change in body temperature at 0.... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL1839203

实验名称：Effective dose on the 8-OH-DPAT induced response at 1 mg/kg sc in presence of 8-OH-DP... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL834580

实验名称：Percent maximal response of 8-OH-DPAT-induced [35S]GTP-gamma-S, binding to 5-HT1A rec... 来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1A External Id：CHEMBL831047

实验名称：Lipophilicity, log D of the compound at pH 7.4 来源：ChEMBL 靶标：N/A External Id：CHEMBL1913207

实验名称：Hypothermic effect in Swiss albino mouse assessed as change in body temperature at 0.... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL1839197

实验名称：Behavioral activity in Wistar rat assessed as reduction of 8-OH-DPAT-induced lower li... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1037435

实验名称：Displacement of [3H]LSD from 5HT2B receptor expressed in HEK293 EBNA cells by radioli... 来源：ChEMBL 靶标：5-hydroxytryptamine receptor 2B External Id：CHEMBL1913217

实验名称：Displacement of [3H]WAY100635 from 5-HT1A receptor (unknown origin) 来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1A External Id：CHEMBL3106306

实验名称：Displacement of [3H]LSD from 5HT7 receptor expressed in HEK293 EBNA cells by radiolig... 来源：ChEMBL 靶标：5-hydroxytryptamine receptor 7 External Id：CHEMBL1913216

实验名称：Agonist activity in forskolin-induced cAMP production in CHO cells expressing 5-HT1A ... 来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1A External Id：CHEMBL837519

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英文别名

• N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)cyclohexanecarboxamide
• N-{2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl}-N-(2-pyridinyl)cyclohexanecarboxamide
• C25H34N4O2.3HCl
• WAY 100,635
• N-(2-(4-(2-Methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide trihydrochloride
• WAY-100,635
• Cyclohexanecarboxamide,N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-2-pyridinyl-,trihydrochloride
• WAY100,635
• WAY 100635 Hydrochloride