Urea, N-[2-[1'-(2,2-dimethylpropyl)-1,2-dihydrospiro[3H-indole-3,4'-piperidin]-1-yl]phenyl]-N'-[4-(trifluoromethoxy)phenyl]

• 常用名: Urea, N-[2-[1'-(2,2-dimethylpropyl)-1,2-dihydrospiro[3H-indole-3,4'-piperidin]-1-yl]phenyl]-N'-[4-(trifluoromethoxy)phenyl]
• 英文名: Urea, N-[2-[1'-(2,2-dimethylpropyl)-1,2-dihydrospiro[3H-indole-3,4'-piperidin]-1-yl]phenyl]-N'-[4-(trifluoromethoxy)phenyl]
• CAS号: 1491839-60-1
• 分子量: 552.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₁H₃₅F₃N₄O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: Urea, N-[2-[1'-(2,2-dimethylpropyl)-1,2-dihydrospiro[3H-indole-3,4'-piperidin]-1-yl]phenyl]-N'-[4-(trifluoromethoxy)phenyl]

物理化学性质

• 分子式: C₃₁H₃₅F₃N₄O₂
• 分子量: 552.6
• InChIKey: FDCUCZZKNTVJSB-UHFFFAOYSA-N
• SMILES: CC(C)(C)CN1CCC2(CC1)CN(c1ccccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1)c1ccccc12

靶点实验

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实验名称：Metabolic stability in human liver microsomes assessed as compound remaining after 10... 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3107680

实验名称：Partition coefficient, log P of the compound at pH 7 by reversed-phase HPLC method 来源：ChEMBL 靶标：N/A External Id：CHEMBL3107681

实验名称：Antagonist activity at P2Y1 receptor in washed human platelets assessed as 1 uM 2-met... 来源：ChEMBL 靶标：P2Y purinoceptor 1 External Id：CHEMBL3107682

实验名称：Antagonist activity at P2Y1 receptor in platelet-enriched human plasma assessed as 2.... 来源：ChEMBL 靶标：P2Y purinoceptor 1 External Id：CHEMBL3107683

实验名称：Displacement of [33P]-2MeS-ADP from human P2Y1 receptor expressed in HEK293 cells aft... 来源：ChEMBL 靶标：P2Y purinoceptor 1 External Id：CHEMBL3107684

实验名称：Oral bioavailability in dog at 0.2 mg/kg 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3107664

实验名称：Fraction unbound in human 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3107665

实验名称：Half life in dog at 0.2 mg/kg, po 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3107666

实验名称：Clearance in dog at 0.2 mg/kg, po and 0.1 mg/kg, iv 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3107667

实验名称：Volume of distribution at steady state in dog at 0.2 mg/kg, po and 0.1 mg/kg, iv 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3107668

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