5-[2-环丙基-1-(2-氟苯基)-2-氧代乙基]-5,6,7,7A-四氢噻吩并[3,2-C]吡啶-2(4H)-酮

• 常用名: 5-[2-环丙基-1-(2-氟苯基)-2-氧代乙基]-5,6,7,7A-四氢噻吩并[3,2-C]吡啶-2(4H)-酮
• 英文名: 5-(2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
• CAS号: 150322-38-6
• 分子量: 331.404
• 密度: 1.4±0.1 g/cm3
• 沸点: 483.6±45.0 °C at 760 mmHg
• 分子式: C₁₈H₁₈FNO₂S
• 熔点: N/A
• 闪点: 246.3±28.7 °C

名称

• 中文名: 5-[2-环丙基-1-(2-氟苯基)-2-氧代乙基]-5,6,7,7a-四氢噻吩并[3,2-c]吡啶-2(4H)-酮
• 英文名: 5-(2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
• 中文别名: 去乙酰普拉格雷 | 5-[2-环丙基-1-(2-氟苯基)-2-氧乙基]-5,6,7,7a-四氢噻吩并[3,2-c]吡啶-2(4H)-酮

物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 483.6±45.0 °C at 760 mmHg
• 分子式: C₁₈H₁₈FNO₂S
• 分子量: 331.404
• 闪点: 246.3±28.7 °C
• 精确质量: 331.104218
• PSA: 62.68000
• LogP: 2.26
• InChIKey: MJAMUSZUMAHFLH-UHFFFAOYSA-N
• SMILES: O=C1C=C2CN(C(C(=O)C3CC3)c3ccccc3F)CCC2S1
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.640
• 储存条件: 2-8°C，避光干燥密封

安全信息

• 海关编码: 2934999090

海关

• 海关编码: 2934999090
• 中文概述: 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

靶点实验

查看更多实验

实验名称：AUC (0 to 2 hrs) in beagle dog treated with 1 mg/kg, portal vein prasugrel 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3539785

实验名称：Drug level in dog intestinal S9 fraction treated with 250 uM prasugrel upto 60 mins i... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3539788

实验名称：Drug level in human intestinal S9 fraction treated with 250 uM prasugrel upto 60 mins... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3539789

实验名称：AUC (0 to 2 hrs) in beagle dog treated with 1 mg/kg, hepatic vein prasugrel 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3539786

实验名称：AUC (0 to 2 hrs) in beagle dog treated with 1 mg/kg, systemic vein prasugrel 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3539787

实验名称：Drug metabolism in human intestinal microsomes assessed as R-138727 formation measure... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3540105

实验名称：Drug metabolism in human liver microsomes assessed as R-138727 formation at 1.6 to 20... 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3540106

实验名称：Drug metabolism in dog intestinal microsomes assessed as R-138727 formation measured ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3540103

实验名称：Drug metabolism in dog liver microsomes assessed as R-138727 formation measured per p... 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3540104

实验名称：Intrinsic clearance in human intestinal microsomes assessed as R-138727 formation mea... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3540109

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英文别名

• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2-one
• 5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
• Prasugrel Impurity 1