4-amino-N-(2,6-dioxo-3-piperidinyl)-2-methoxyBenzamide

• 常用名: 4-amino-N-(2,6-dioxo-3-piperidinyl)-2-methoxyBenzamide
• 英文名: 4-amino-N-(2,6-dioxo-3-piperidinyl)-2-methoxyBenzamide
• CAS号: 1504209-32-8
• 分子量: 277.28
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₃H₁₅N₃O₄
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 4-amino-N-(2,6-dioxo-3-piperidinyl)-2-methoxyBenzamide

物理化学性质

• 分子式: C₁₃H₁₅N₃O₄
• 分子量: 277.28
• InChIKey: SLGDHJMSLPDYEO-UHFFFAOYSA-N
• SMILES: COc1cc(N)ccc1C(=O)NC1CCC(=O)NC1=O

靶点实验

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实验名称：Induction of CK1alpha degradation in human MM1.S cells at 0.1 uM incubated for 16 hrs... 来源：ChEMBL 靶标：Casein kinase I isoform alpha External Id：CHEMBL5374918

实验名称：Induction of GSPT1 degradation in human MM1.S cells at 0.1 uM incubated for 16 hrs by... 来源：ChEMBL 靶标：Eukaryotic peptide chain release factor GTP-binding subunit ERF3A External Id：CHEMBL5374919

实验名称：Induction of SALL4 degradation in human HuH-6 cells at 0.1 uM incubated for 16 hrs by... 来源：ChEMBL 靶标：Protein cereblon External Id：CHEMBL5374916

实验名称：Aqueous stability of the compound in PBS at pH 7 to 9 at 50 uM incubated for 4 hrs by... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5374914

实验名称：Induction of IKZF3 degradation in human MM1.S cells at 0.1 uM incubated for 16 hrs by... 来源：ChEMBL 靶标：Zinc finger protein Aiolos External Id：CHEMBL5374915

实验名称：Redox activity of the compound assessed as ROS generation using H2DCFDA as substrate ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5374912

实验名称：Redox activity of the compound assessed as free radicals generation using H2DCFDA as ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5374913

实验名称：Plasma Protein binding in human albumin assessed as fraction bound by rapid equlibriu... 来源：ChEMBL 靶标：Albumin External Id：CHEMBL5374910

实验名称：Chromatographic hydrophobicity index, CHI of the compound at pH 7.4 by HPLC analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL5374911

实验名称：Binding affinity to human CRBN TBD assessed as inhibition constant using BODIPY-uraci... 来源：ChEMBL 靶标：Protein cereblon External Id：CHEMBL5374908

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