4-[4-(4-Fluorophenyl)-2-[4-(methylthio)phenyl]-1H-imidazol-5-yl]pyridine

• 常用名: 4-[4-(4-Fluorophenyl)-2-[4-(methylthio)phenyl]-1H-imidazol-5-yl]pyridine
• 英文名: 4-[4-(4-Fluorophenyl)-2-[4-(methylthio)phenyl]-1H-imidazol-5-yl]pyridine
• CAS号: 152121-44-3
• 分子量: 361.43500
• 密度: 1.346g/cm3
• 沸点: 560.875ºC at 760 mmHg
• 分子式: C₂₁H₁₆FN₃S
• 熔点: N/A
• 闪点: 293.007ºC

名称

• 英文名: 4-[4-(4-fluorophenyl)-2-(4-methylsulfanylphenyl)-1H-imidazol-5-yl]pyridine

物理化学性质

• 密度: 1.346g/cm3
• 沸点: 560.875ºC at 760 mmHg
• 分子式: C₂₁H₁₆FN₃S
• 分子量: 361.43500
• 闪点: 293.007ºC
• 精确质量: 361.10500
• PSA: 66.87000
• LogP: 5.66670
• InChIKey: ZPXPEKQMLOAPLT-UHFFFAOYSA-N
• SMILES: CSc1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1
• 蒸汽压: 0mmHg at 25°C
• 折射率: 1.694

靶点实验

查看更多实验

实验名称：Binding affinity towards human glucagon receptor in absence of Mg2+ expressed as IC50 来源：ChEMBL 靶标：Glucagon receptor External Id：CHEMBL684123

实验名称：Binding affinity towards human Mitogen-activated protein kinase p38 expressed as IC50 来源：ChEMBL 靶标：Mitogen-activated protein kinase 11 External Id：CHEMBL732095

实验名称：Inhibitory activity against 5-lipoxygenase enzyme from RBL-1 cells 来源：ChEMBL 靶标：Polyunsaturated fatty acid 5-lipoxygenase External Id：CHEMBL882929

实验名称：Inhibitory activity against p38-alpha kinase 来源：ChEMBL 靶标：Mitogen-activated protein kinase 14 External Id：CHEMBL842195

实验名称：ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake fl... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301363

实验名称：Binding affinity determined by reduction in binding of 125 I-glucagon to the human gl... 来源：ChEMBL 靶标：Glucagon receptor External Id：CHEMBL684119

实验名称：Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocy... 来源：ChEMBL 靶标：Polyunsaturated fatty acid 5-lipoxygenase External Id：CHEMBL697605

实验名称：Antagonist activity at human glucagon receptor 来源：ChEMBL 靶标：Glucagon receptor External Id：CHEMBL2437506

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英文别名

• Kinome_3427