(S)-N8-Hydroxy-2-((R)-5-oxopyrrolidine-2-carboxamido)-N1-(3-(trifluoromethyl)phenyl)octanediamide

• 常用名: (S)-N8-Hydroxy-2-((R)-5-oxopyrrolidine-2-carboxamido)-N1-(3-(trifluoromethyl)phenyl)octanediamide
• 英文名: (S)-N8-Hydroxy-2-((R)-5-oxopyrrolidine-2-carboxamido)-N1-(3-(trifluoromethyl)phenyl)octanediamide
• CAS号: 1528755-83-0
• 分子量: 458.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₂₅F₃N₄O₅
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (S)-N8-Hydroxy-2-((R)-5-oxopyrrolidine-2-carboxamido)-N1-(3-(trifluoromethyl)phenyl)octanediamide

物理化学性质

• 分子式: C₂₀H₂₅F₃N₄O₅
• 分子量: 458.4
• InChIKey: XVGBJXUAVWXLJX-LSDHHAIUSA-N
• SMILES: O=C(CCCCCC(NC(=O)C1CCC(=O)N1)C(=O)Nc1cccc(C(F)(F)F)c1)NO

靶点实验

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实验名称：Inhibition of human HDAC2 using RHKK(Ac) as substrate by fluorimetric analysis 来源：ChEMBL 靶标：Histone deacetylase 2 External Id：CHEMBL3376039

实验名称：Inhibition of human HDAC1 using RHKK(Ac) as substrate by fluorimetric analysis 来源：ChEMBL 靶标：Histone deacetylase 1 External Id：CHEMBL3376038

实验名称：Inhibition of human HDAC6 using RHKK(Ac) as substrate by fluorimetric analysis 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL3376041

实验名称：Inhibition of human HDAC3 using RHKK(Ac) as substrate by fluorimetric analysis 来源：ChEMBL 靶标：Histone deacetylase 3 External Id：CHEMBL3376040

实验名称：Inhibition of human HDAC10 using RHKK(Ac) as substrate by fluorimetric analysis 来源：ChEMBL 靶标：Polyamine deacetylase HDAC10 External Id：CHEMBL3376043

实验名称：Inhibition of human HDAC8 using RHK(Ac)K(Ac) as substrate by fluorimetric analysis 来源：ChEMBL 靶标：Histone deacetylase 8 External Id：CHEMBL3376042

实验名称：Cytotoxicity against human NCI-H460 cells 来源：ChEMBL 靶标：NCI-H460 External Id：CHEMBL3376045

实验名称：Inhibition of human HDAC11 using RHKK(Ac) as substrate by fluorimetric analysis 来源：ChEMBL 靶标：Histone deacetylase 11 External Id：CHEMBL3376044

实验名称：Antiprotozoan activity against Trypanosoma cruzi Tulahuen C4 amastigotes 来源：ChEMBL 靶标：Trypanosoma cruzi External Id：CHEMBL3376047

实验名称：Antiprotozoan activity against Trypanosoma brucei rhodesiense STIB 900 trypomastigote... 来源：ChEMBL 靶标：Trypanosoma brucei rhodesiense External Id：CHEMBL3376046

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