盐酸非索非那定

• 常用名: 盐酸非索非那定
• 英文名: Fexofenadine hydrochloride
• CAS号: 153439-40-8
• 分子量: 538.117
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₂H₄₀ClNO₄
• 熔点: 148-150oC
• 闪点: N/A

盐酸非索非那定用途

Fexofenadine是第三代抗组胺药，用于治疗过敏症状，如花粉热，鼻塞和荨麻疹。

盐酸非索非那定名称

• 中文名: 盐酸非索非那定
• 英文名: Fexofenadine Hydrochloride
• 中文别名: 非索非那定盐酸盐 | Benzeneacetic acid, 4-​[1-​hydroxy-​4-​[4-​(hydroxydiphenylmeth​yl)​-​1-​piperidinyl]​butyl]​-​α,​α-​dimethyl-​, hydrochloride

盐酸非索非那定生物活性

• 描述: Fexofenadine是第三代抗组胺药,用于治疗过敏症状,如花粉热,鼻塞和荨麻疹。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 组胺受体
  信号通路 >> 免疫及炎症 >> 组胺受体
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Bachert C, et al. A review of the efficacy of desloratadine, fexofenadine, and levocetirizine in the treatment of nasal congestion in patients with allergic rhinitis. Clin Ther 31 (5): 921-44.

  [2]. Compalati E, et al. Systematic review on the efficacy of fexofenadine in seasonal allergic rhinitis: a meta-analysis of randomized, double-blind, placebo-controlled clinical trials.". International Archives of Allergy and Immunology 156 (1): 1-15.

盐酸非索非那定物理化学性质

• 熔点: 148-150oC
• 分子式: C₃₂H₄₀ClNO₄
• 分子量: 538.117
• 精确质量: 537.264587
• PSA: 81.00000
• LogP: 6.25040
• 外观性状: 固体;White to Almost white powder to crystal
• 储存条件: −20°C
• 水溶解性: 可溶于：甲醇

盐酸非索非那定安全信息

• 个人防护装备: Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
• 危害码 (欧洲): Xi
• 风险声明 (欧洲): 36/37/38
• 安全声明 (欧洲): 26-36
• 危险品运输编码: NONH for all modes of transport

盐酸非索非那定英文别名

• 2-[4-(1-Hydroxy-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}butyl)phenyl]-2-methylpropansäurehydrochlorid
• Fexofenidine hydrochloride MDL 16455 hydrochloride Terfenidine carboxylate hydrochloride
• Benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-, hydrochloride (1:1)
• Fexofenadine HCl
• Fexofenadine hydrochloride
• benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-, hydrochloride
• Fexofenidine hydrochloride,MDL 16455 hydrochloride,Terfenidine carboxylate hydrochloride
• 2-[4-(1-Hydroxy-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}butyl)phenyl]-2-methylpropanoic acid hydrochloride (1:1)
• acide 2-[4-(1-hydroxy-4-{4-[hydroxy(diphényl)méthyl]pipéridin-1-yl}butyl)phényl]-2-méthylpropanoïque chlorhydrate
• MFCD08064193
• UNII:2S068B75ZU
• 2-[4-(1-hydroxy-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}butyl)phenyl]-2-methylpropanoic acid hydrochloride
• 2-[4-(1-Hydroxy-4-{4-[hydroxy(diphenyl)methyl]-1-piperidinyl}butyl)phenyl]-2-methylpropanoic acid hydrochloride (1:1)
• benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-a,a-dimethyl-, hydrochloride (1:1)
• Benzeneacetic acid, 4-​[1-​hydroxy-​4-​[4-​(hydroxydiphenylmeth​yl)​-​1-​piperidinyl]​butyl]​-​α,​α-​dimethyl-​, hydrochloride
• Fexofenadine (hydrochloride)