3’-beta-C-Methyladenosine

• 常用名: 3’-beta-C-Methyladenosine
• 英文名: 3’-beta-C-Methyladenosine
• CAS号: 15397-13-4
• 分子量: 281.27
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₁H₁₅N₅O₄
• 熔点: N/A
• 闪点: N/A

3’-beta-C-Methyladenosine用途

3′-β-C甲基腺苷是一种腺苷类似物。腺苷类似物主要起到平滑肌血管扩张剂的作用,也被证明可以抑制癌症的进展。该系列中流行的产品有磷酸腺苷、阿卡地辛(HY-13417)、氯法拉滨(HY-A0005)、磷酸氟达拉滨(HY-B0028)和维达拉宾(HY-B0277)[1]。

3’-beta-C-Methyladenosine名称

• 英文名: 5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-3-methyloxolane-3,4-diol

3’-beta-C-Methyladenosine生物活性

• 描述: 3′-β-C甲基腺苷是一种腺苷类似物。腺苷类似物主要起到平滑肌血管扩张剂的作用,也被证明可以抑制癌症的进展。该系列中流行的产品有磷酸腺苷、阿卡地辛(HY-13417)、氯法拉滨(HY-A0005)、磷酸氟达拉滨(HY-B0028)和维达拉宾(HY-B0277)[1]。
• 相关类别:
  信号通路 >> 细胞周期/DNA损伤 >> 核苷抗代谢药/类似物
  研究领域 >> 其他
• 参考文献:

  [1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

3’-beta-C-Methyladenosine物理化学性质

• 分子式: C₁₁H₁₅N₅O₄
• 分子量: 281.27
• 精确质量: 281.11200
• PSA: 139.54000
• InChIKey: MLIWWOXSMXQECL-ZGUVBZSNSA-N
• SMILES: CC1(O)C(CO)OC(n2cnc3c(N)ncnc32)C1O

3’-beta-C-Methyladenosine靶点实验

查看更多实验

实验名称：Induction of cell cycle arrest in human HL60 cells assessed as accumulation at G1 pha... 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL3381359

实验名称：Induction of cell cycle arrest in human HL60 cells assessed as accumulation at G2M ph... 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL3381358

实验名称：Inhibitory activity against Adenosine A2A receptor by inhibition of [3H]-CGS- 21680 b... 来源：ChEMBL 靶标：Adenosine receptor A2a External Id：CHEMBL642122

实验名称：Induction of cell cycle arrest in human HL60 cells assessed as accumulation at G2M ph... 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL3381361

实验名称：Inhibitory activity at Adenosine A1 receptor by inhibition of [3H]CHA binding to bovi... 来源：ChEMBL 靶标：Adenosine receptor A1 External Id：CHEMBL637553

实验名称：Induction of cell cycle arrest in human HL60 cells assessed as accumulation at S phas... 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL3381360

实验名称：Antiproliferative activity against human HeLa cells after 72 hrs by MTS assay 来源：ChEMBL 靶标：HeLa External Id：CHEMBL1775980

实验名称：Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL1775982

实验名称：Antiproliferative activity against human K562 cells after 72 hrs by MTS assay 来源：ChEMBL 靶标：K562 External Id：CHEMBL1775981

实验名称：Binding affinity to adenosine A1 receptor in rat brain membranes by measuring displac... 来源：ChEMBL 靶标：Adenosine receptor A1 External Id：CHEMBL875796

共43条，当前第1页，共5页

1

2

3

4

5

3’-beta-C-Methyladenosine英文别名

• 3'-methyl-adenosine