瑞舒伐他汀中间体C-4结构式
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常用名 | 瑞舒伐他汀中间体C-4 | 英文名 | (4R-Cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-aceticacid,1,1-dimethylethylester |
|---|---|---|---|---|
| CAS号 | 154026-95-6 | 分子量 | 302.363 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 353.1±22.0 °C at 760 mmHg | |
| 分子式 | C15H26O6 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | 150.3±22.4 °C |
| 中文名 | (4R-cis)-6-[(乙酰氧基)甲基]-2,2-二甲基-1,3-二氧六环-4-乙酸叔丁酯 |
|---|---|
| 英文名 | tert-Butyl (4R-cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetate |
| 中文别名 | 罗素伐他汀钙中间体 C-1 | 1 D-5(4R-CIS)-6-[(乙酰氧基)甲基]-2,2-二甲基-1,3-二氧六环-4-乙酸叔丁酯 | 2-[(4R,6S)-2,2-二甲基-6-(乙酰氧甲基)-1,3-二噁烷-4-基]乙酸叔丁酯 | 6-乙酰氧甲基-2,2-二甲基-1,3-二氧戊环-乙酸叔丁酯 (瑞舒伐他汀中间体) | 4R-顺-6-乙酰氧基甲基-2,2-二甲基-1,3-二氧杂-4-乙酸异丙酯(D5) | 瑞舒伐他汀钙杂质 01 |
| 英文别名 | 更多 |
| 密度 | 1.0±0.1 g/cm3 |
|---|---|
| 沸点 | 353.1±22.0 °C at 760 mmHg |
| 分子式 | C15H26O6 |
| 分子量 | 302.363 |
| 闪点 | 150.3±22.4 °C |
| 精确质量 | 302.172943 |
| PSA | 71.06000 |
| LogP | 2.18 |
| 外观性状 | 白色或灰白色固体粉末 |
| 蒸汽压 | 0.0±0.8 mmHg at 25°C |
| 折射率 | 1.436 |
| 储存条件 | 2-8°C |
| 危害码 (欧洲) | Xi |
|---|---|
| 海关编码 | 2932999099 |
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~78%
瑞舒伐他汀中间体C-4 154026-95-6 |
| 文献:DSM IP ASSESTS B.V. Patent: WO2003/106447 A1, 2003 ; Location in patent: Page 5 ; |
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~99%
瑞舒伐他汀中间体C-4 154026-95-6 |
| 文献:BAKHU PHARMA LIMITED; PROCTOR, Lee David; GREIG, Stuart Alexander James Patent: WO2012/17242 A1, 2012 ; Location in patent: Page/Page column 20 ; |
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瑞舒伐他汀中间体C-4 154026-95-6 |
| 文献:WO2012/17242 A1, ; Page/Page column 14 ; |
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~%
瑞舒伐他汀中间体C-4 154026-95-6 |
| 文献:Fan, Weizheng; Li, Wanfang; Ma, Xin; Tao, Xiaoming; Li, Xiaoming; Yao, Ying; Xie, Xiaomin; Zhang, Zhaoguo Journal of Organic Chemistry, 2011 , vol. 76, # 22 p. 9444 - 9451 |
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瑞舒伐他汀中间体C-4 154026-95-6 |
| 文献:WO2012/17242 A1, ; Page/Page column 11-12 ; |
| 海关编码 | 2932999099 |
|---|---|
| 中文概述 | 2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途 |
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| (4R,6S)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid |
| tert-butyl 6-O-acetyl-2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate |
| tert-Butyl (4R-cis) |
| 6S)-6-(acetoxyMethyl)-2 |
| (4R-CIS)-6-[ (ACETYLOXY)METHYL ]-2,2-DIMETHYL-1 |
| 1,1-dimethylethylester |
| D-erythro-Hexonic acid, 2,4-dideoxy-3,5-O-(1-methylethylidene)-, 1,1-dimethylethyl ester, acetate |
| MFCD08458213 |
| tert-butyl 2-[(4R,6S)-6-(acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate |
| tert-Butyl(4R-cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetate |
| tert-Butyl 6-O-acetyl-2,4-dideoxy-3,5-O-isopropylidene-D-erythro-hexonate |
| tert-butyl 2-((4R |
| 3-dioxan-4-yl)acetate |
| (4R-cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid,1,1-dimethylethyl ester |
| 2-Methyl-2-propanyl 6-O-acetyl-2,4-dideoxy-3,5-O-isopropylidene-D-erythro-hexonate |
| (4R-CIS)-6-[(ACETYLOXY)METHYL]-2,2-DIMETHYL-1,3-DIOXANE-4-ACETIC ACID,T-BUTYL ESTER |
| rosuvastatin interMediates D-5 |
| tert-butyl 2-{(4R,6S)-2,2-dimethyl-6-[(methyl-carbonyloxy)methyl]-1,3-dioxan-4-yl} acetate |
| 2-[(4R,6S)-6-(Acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetic acid tert-buthyl ester |
| (4R-Cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-aceticacid,1,1-dimethylethylester |