比马酰胺

• 常用名: 比马酰胺
• 英文名: N-Desethyl Bimatoprost
• CAS号: 155205-89-3
• 分子量: 387.512
• 密度: 1.2±0.1 g/cm3
• 沸点: 618.3±55.0 °C at 760 mmHg
• 分子式: C₂₃H₃₃NO₄
• 熔点: N/A
• 闪点: 327.7±31.5 °C

比马酰胺用途

N-去乙基比马前列素是比马前列腺素(HY-B0191)的N-去乙基代谢物[1]。

比马酰胺名称

• 中文名: 比马酰胺
• 英文名: 17-phenyl trinor prostaglandin f2alpha amide

比马酰胺生物活性

• 描述: N-去乙基比马前列素是比马前列腺素(HY-B0191)的N-去乙基代谢物[1]。
• 相关类别:
  研究领域 >> 其他
• 参考文献:

  [1]. Edward Dunne Corboy, et al. Topical application of dihydrotestosterone for promoting hair growth containing formulations. US20140162992A1.

比马酰胺物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 618.3±55.0 °C at 760 mmHg
• 分子式: C₂₃H₃₃NO₄
• 分子量: 387.512
• 闪点: 327.7±31.5 °C
• 精确质量: 387.240967
• PSA: 103.78000
• LogP: 1.27
• InChIKey: RAGQWYIPCPFTJC-KDACTHKWSA-N
• SMILES: NC(=O)CCCC=CCC1C(O)CC(O)C1C=CC(O)CCc1ccccc1
• 蒸汽压: 0.0±1.9 mmHg at 25°C
• 折射率: 1.615
• 储存条件: -20°C， 充氩

比马酰胺靶点实验

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实验名称：GPR151 activator identification: cell-based high-throughput counter-screen assay 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Glucose-dependent insulinotropic receptor; AltName: Full=G-protein coupled receptor 119 External Id：GPR119_PHUNTER_AG_LUMI_1536_3X%ACT CSRUN1

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：GPR151 activator identification: cell-based high-throughput confirmation assay 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_3X%ACT CRUN1

实验名称：A screen for small molecules that modulate mitochondrial supercomplex formation 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1482

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

实验名称：Stabilization of p53 in human papillomavirus-positive cells 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Cellular tumor antigen p53 External Id：HMS1485

实验名称：Discovering small molecule activators of G protein-gated inwardly-rectifying potassiu... 来源：15621 靶标：G protein-activated inward rectifier potassium channel 2 External Id：VANDERBILT_HTS_GIRK2_MPD

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比马酰胺英文别名

• 9alpha,11alpha,15s-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5z,13e-dien-1-amide
• (5Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl}-5-heptenamide