PS10

更新时间：2025-08-25 09:10:47

PS10结构式	常用名	PS10	英文名	PS10
	CAS号	1564265-82-2	分子量	323.319
	密度	N/A	沸点	N/A
	分子式	C₁₄H₁₃NO₆S	熔点	N/A
	MSDS	N/A	闪点	N/A

PS10用途

PS10(PDK抑制剂PS10)是一种新型有效且高选择性的丙酮酸脱氢酶激酶(PDK)抑制剂；改善葡萄糖耐量,刺激饮食诱导的肥胖中的心肌碳水化合物氧化；PS10是更适合治疗糖尿病性心肌病的PDK抑制剂。

英文名	PS10

描述	PS10(PDK抑制剂PS10)是一种新型有效且高选择性的丙酮酸脱氢酶激酶(PDK)抑制剂；改善葡萄糖耐量,刺激饮食诱导的肥胖中的心肌碳水化合物氧化；PS10是更适合治疗糖尿病性心肌病的PDK抑制剂。
参考文献	References 1. Wu CY, et al. J Biol Chem. 2018 May 8. pii: jbc.RA118.002838. View Related Products by Target Pyruvate Dehydrogenase Kinase (PDK)

分子式	C₁₄H₁₃NO₆S
分子量	323.319
InChIKey	SVUZJWAAXPEMKJ-UHFFFAOYSA-N
SMILES	O=S(=O)(c1ccc(O)cc1O)N1Cc2cc(O)cc(O)c2C1

实验名称：Apparent clearance in CD1 mouse muscle at 70 mg/kg, ip by LC-MS/MS analysis
来源：ChEMBL
靶标：N/A
External Id：CHEMBL3998703

实验名称：Apparent volume of distribution during terminal phase in CD1 mouse muscle at 70 mg/kg...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL3998702

实验名称：Apparent clearance in in CD1 mouse plasma at 70 mg/kg, ip by LC-MS/MS analysis
来源：ChEMBL
靶标：Plasma
External Id：CHEMBL3998691

实验名称：Apparent volume of distribution during terminal phase in CD1 mouse plasma at 70 mg/kg...
来源：ChEMBL
靶标：Plasma
External Id：CHEMBL3998690

实验名称：Cmax in CD1 mouse liver at 70 mg/kg, ip by LC-MS/MS analysis
来源：ChEMBL
靶标：Liver
External Id：CHEMBL3998693

实验名称：Terminal half life in CD1 mouse liver at 70 mg/kg, ip by LC-MS/MS analysis
来源：ChEMBL
靶标：Liver
External Id：CHEMBL3998692

实验名称：Terminal half life in CD1 mouse plasma at 70 mg/kg, ip by LC-MS/MS analysis
来源：ChEMBL
靶标：Plasma
External Id：CHEMBL3998686

实验名称：AUClast in CD1 mouse plasma at 70 mg/kg, ip by LC-MS/MS analysis
来源：ChEMBL
靶标：Plasma
External Id：CHEMBL3998689

实验名称：Inhibition of PDK4 in HEK293T cells assessed as reduction in PDHE1alpha phosphorylati...
来源：ChEMBL
靶标：[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial
External Id：CHEMBL4333051

实验名称：Tmax in CD1 mouse plasma at 70 mg/kg, ip by LC-MS/MS analysis
来源：ChEMBL
靶标：Plasma
External Id：CHEMBL3998688

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