4-(4-氟苯基)-3-(4-甲基磺酰基苯基)-2H-呋喃-5-酮

• 常用名: 4-(4-氟苯基)-3-(4-甲基磺酰基苯基)-2H-呋喃-5-酮
• 英文名: 3-(4-fluorophenyl)-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one
• CAS号: 157672-00-9
• 分子量: 332.34600
• 密度: 1.385±0.06 g/cm3(Predicted)
• 沸点: 571.3±50.0 °C(Predicted)
• 分子式: C₁₇H₁₃FO₄S
• 熔点: 170-171 °C
• 闪点: N/A

名称

• 中文名: 4-(4-氟苯基)-3-(4-甲基磺酰基苯基)-2H-呋喃-5-酮
• 英文名: 4-(4-fluorophenyl)-3-(4-methylsulfonylphenyl)-2H-furan-5-one

物理化学性质

• 密度: 1.385±0.06 g/cm3(Predicted)
• 沸点: 571.3±50.0 °C(Predicted)
• 熔点: 170-171 °C
• 分子式: C₁₇H₁₃FO₄S
• 分子量: 332.34600
• 精确质量: 332.05200
• PSA: 68.82000
• LogP: 3.77760
• InChIKey: ZRCURVJXQGLLOZ-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)c1ccc(C2=C(c3ccc(F)cc3)C(=O)OC2)cc1
• 储存条件: 室温

靶点实验

查看更多实验

实验名称：Ratio of Cyclooxygenase-1 to Cyclooxygenase-2 来源：ChEMBL 靶标：N/A External Id：CHEMBL852250

实验名称：Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay 来源：ChEMBL 靶标：PC-3 External Id：CHEMBL2404354

实验名称：Inhibition of ovine COX-1 assessed as using arachidonic acid as substrate at 10 uM pr... 来源：ChEMBL 靶标：Prostaglandin G/H synthase 1 External Id：CHEMBL2406827

实验名称：Antiproliferative activity against human DU145 cells after 72 hrs by MTT assay 来源：ChEMBL 靶标：DU-145 External Id：CHEMBL2406841

实验名称：Inhibition of ovine COX-2 assessed as using arachidonic acid as substrate at 10 uM pr... 来源：ChEMBL 靶标：Prostaglandin G/H synthase 2 External Id：CHEMBL2406829

实验名称：Antiproliferative activity against human PC3 cells expressing SKP2 after 72 hrs by MT... 来源：ChEMBL 靶标：PC-3 External Id：CHEMBL2404356

实验名称：Inhibition of ovine COX-2 assessed as using arachidonic acid as substrate preincubate... 来源：ChEMBL 靶标：Prostaglandin G/H synthase 2 External Id：CHEMBL2406828

实验名称：Antiproliferative activity against human PC3 cells expressing PCDNA after 72 hrs by M... 来源：ChEMBL 靶标：PC-3 External Id：CHEMBL2404355

实验名称：Ratio of IC50 values at Cyclooxygenase-1 and Cyclooxygenase-2 来源：ChEMBL 靶标：N/A External Id：CHEMBL848592

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英文别名

• 3-(4-Fluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2-(5H)-furanone
• 3-(4-fluorophenyl)-4-(4-methanesulfonylphenyl)-5H-furan-2-one
• 3-(4-fluorophenyl)-4-[(4-methylsulfonyl)phenyl]-5H-furan-2-one
• 3-(4-Fluorophenyl)-4-[4-(methylsulfonyl)phenyl]-5-hydrofuran-2-one
• 2(5H)-Furanone,3-(4-fluorophenyl)-4-[4-(methylsulfonyl)phenyl]