1-BOC-4-氰基-4-苯基哌啶

更新时间：2025-08-25 17:51:55

1-BOC-4-氰基-4-苯基哌啶结构式	常用名	1-BOC-4-氰基-4-苯基哌啶	英文名	tert-butyl 4-cyano-4-phenylpiperidine-1-carboxylate
	CAS号	158144-79-7	分子量	286.369
	密度	1.119g/cm3	沸点	426.047°C at 760 mmHg
	分子式	C₁₇H₂₂N₂O₂	熔点	N/A
	MSDS	N/A	闪点	211.5±28.7 °C

中文名	4-氰基-4-苯基哌啶-1-羧酸叔丁酯
英文名	tert-butyl 4-cyano-4-phenylpiperidine-1-carboxylate
中文别名	1-BOC-4-氰基-4-苯基哌啶 \| 2-甲基-2-丙基4-氰基-4-苯基-1-哌啶羧酸酯
英文别名	更多

密度	1.119g/cm3
沸点	426.047°C at 760 mmHg
分子式	C₁₇H₂₂N₂O₂
分子量	286.369
闪点	211.5±28.7 °C
精确质量	286.168121
PSA	53.33000
LogP	2.69
InChIKey	QZJPNISMAWIZOO-UHFFFAOYSA-N
SMILES	CC(C)(C)OC(=O)N1CCC(C#N)(c2ccccc2)CC1
蒸汽压	0.0±1.0 mmHg at 25°C
折射率	1.549

4-氰基-4-苯基哌啶

40481-13-8

二碳酸二叔丁酯

24424-99-5

~99%

1-BOC-4-氰基-4-苯基哌啶

158144-79-7

文献：BRISTOL-MYERS SQUIBB COMPANY Patent: WO2008/124757 A1, 2008 ; Location in patent: Page/Page column 51-52 ; WO 2008/124757 A1

二碳酸二叔丁酯

24424-99-5

4-氰基-4-苯基哌嗪

51304-58-6

~96%

1-BOC-4-氰基-4-苯基哌啶

158144-79-7

文献：Duan, Maosheng; Aquino, Christopher; Ferris, Robert; Kazmierski, Wieslaw M.; Kenakin, Terry; Koble, Cecilia; Wheelan, Pat; Watson, Chris; Youngman, Michael Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1610 - 1613

碳酸二叔丁酯

34619-03-9

4-氰基-4-苯基哌嗪

51304-58-6

~10%

1-BOC-4-氰基-4-苯基哌啶

158144-79-7

文献：SMITHKLINE BEECHAM CORPORATION Patent: WO2004/54974 A2, 2004 ; Location in patent: Page 48 ; WO 2004/054974 A2

苯乙腈

140-29-4

N,N-双(2-氯乙基)氨基甲酸叔丁酯

118753-70-1

1-BOC-4-氰基-4-苯基哌啶

158144-79-7

文献：Kuduk, Scott D.; Chang, Ronald K.; Di Marco, Christina N.; Pitts, Daniel R.; Greshock, Thomas J.; Ma, Lei; Wittmann, Marion; Seager, Matthew A.; Koeplinger, Kenneth A.; Thompson, Charles D.; Hartman, George D.; Bilodeau, Mark T.; Ray, William J. Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4773 - 4780

1-N-BOC-4-PHENYLPIPERIDINE-4-CARBONITRILE

1-Boc-4-phenyl-4-piperidinecarbonitrile

2-Methyl-2-propanyl 4-cyano-4-phenyl-1-piperidinecarboxylate

Tert-butyl 4-cyano-4-phenyl-piperidine-1-carboxylate

TERT-BUTYL 4-CYANO-4-PHENYL-1-PIPERIDINECARBOXYLATE

1-Piperidinecarboxylic acid, 4-cyano-4-phenyl-, 1,1-dimethylethyl ester

N-(tert-butoxycarbonyl)-4-phenyl-4-cyanopiperidine

1-Boc-4-cyano-4-phenylpiperidine

4-cyano-4-phenyl-piperidine-1-carboxylic acid tert-butyl ester

MFCD09056769