L-749372

• 常用名: L-749372
• 英文名: L-749372
• CAS号: 159183-70-7
• 分子量: 553.41
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₂H₂₄IN₃O₄S
• 熔点: N/A
• 闪点: N/A

L-749372用途

L-749372是β3肾上腺素受体3-吡啶氧基丙醇胺激动剂。

L-749372名称

• 英文名: L-749372

L-749372生物活性

• 描述: L-749372是β3肾上腺素受体3-吡啶氧基丙醇胺激动剂。
• 参考文献: 1. Weber AE, Ok HO, Alvaro RF, Candelore MR, Cascieri MA, Chiu SH, Deng L, Forrest MJ, Hom GJ, Hutchins JE, Kao J, MacIntyre DE, Mathvink RJ, McLoughlin D, Miller RR, Newbold RC, Olah TV, Parmee ER, Perkins L, Stearns RA, Strader CD, Szumiloski J, Tang YS, Tota L, Fisher MH, et al. 3-Pyridyloxypropanolamine agonists of the beta 3 adrenergic receptor with improved pharmacokinetic properties. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2111-6. PubMed PMID: 9873496.

L-749372物理化学性质

• 分子式: C₂₂H₂₄IN₃O₄S
• 分子量: 553.41
• InChIKey: JKCIKWIXDFDPQX-FQEVSTJZSA-N
• SMILES: O=S(=O)(Nc1ccc(CCNCC(O)COc2cccnc2)cc1)c1ccc(I)cc1

L-749372靶点实验

查看更多实验

实验名称：Agonism of human beta-3 adrenergic receptor 来源：ChEMBL 靶标：Beta-3 adrenergic receptor External Id：CHEMBL653154

实验名称：Selectivity ratio of EC50 for Homo sapiens (human) beta1 adrenoreceptor to EC50 for H... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3059442

实验名称：Agonist activity at Homo sapiens (human) beta3 adrenoreceptor 来源：ChEMBL 靶标：Beta-3 adrenergic receptor External Id：CHEMBL3059443

实验名称：Agonist activity at Homo sapiens (human) beta3 adrenoreceptor relative to control 来源：ChEMBL 靶标：Beta-3 adrenergic receptor External Id：CHEMBL3059444

实验名称：Agonism against Beta-3 adrenergic receptor 来源：ChEMBL 靶标：Beta-3 adrenergic receptor External Id：CHEMBL652340

实验名称：Evaluated for its agonist activity against human Beta-3 adrenergic receptor 来源：ChEMBL 靶标：Beta-3 adrenergic receptor External Id：CHEMBL652342

实验名称：Bioavailability in dog 来源：ChEMBL 靶标：N/A External Id：CHEMBL629575

实验名称：Evaluated for its agonist activity and the binding affinity against human Beta-1 adre... 来源：ChEMBL 靶标：Beta-1 adrenergic receptor External Id：CHEMBL649968

实验名称：Effective dose to stimulate lipolysis in Rhesus monkeys(iv) 来源：ChEMBL 靶标：Macaca mulatta External Id：CHEMBL801944

实验名称：Evaluated for its agonist activity and the binding affinity against human Beta-2 adre... 来源：ChEMBL 靶标：Beta-2 adrenergic receptor External Id：CHEMBL647874

共12条，当前第1页，共2页

1

2