碘西他酸

• 常用名: 碘西他酸
• 英文名: iocetamic acid (200 mg)
• CAS号: 16034-77-8
• 分子量: 613.95700
• 密度: 2.416g/cm3
• 沸点: 658.2ºC at 760 mmHg
• 分子式: C₁₂H₁₃I₃N₂O₃
• 熔点: 224-225ºC
• 闪点: 351.9ºC

碘西他酸用途

胆盐水(DRC 1201)是一种诊断辅助剂,是一种口服活性造影剂[1]。

碘西他酸名称

• 中文名: 碘西他酸
• 英文名: 3-(N-acetyl-3-amino-2,4,6-triiodoanilino)-2-methylpropanoic acid
• 中文别名: 3-(N-(3-氨基-2,4,6-三碘苯基)乙酰氨基)-2-甲基丙酸

碘西他酸生物活性

• 描述: 胆盐水(DRC 1201)是一种诊断辅助剂,是一种口服活性造影剂[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 体内研究: 胆盐水在大鼠中 LD50型为 7克/千克(口服) 和 0.7克/千克(静脉注射)[2].
• 参考文献:

  [1]. Owen JP, et al. Comparative study of iocetamic acid and calcium ipodate in the visualisation of the gallbladder and common bile duct. Clin Radiol. 1978 Sep;29(5):535-40.

  [2]. Janbroers JM, et al. Toxicologic studies of iocetamic acid in rats and dogs. Toxicol Appl Pharmacol. 1969 Mar;14(2):242-8.

碘西他酸物理化学性质

• 密度: 2.416g/cm3
• 沸点: 658.2ºC at 760 mmHg
• 熔点: 224-225ºC
• 分子式: C₁₂H₁₃I₃N₂O₃
• 分子量: 613.95700
• 闪点: 351.9ºC
• 精确质量: 613.80600
• PSA: 83.63000
• LogP: 3.73740
• InChIKey: GSVQIUGOUKJHRC-UHFFFAOYSA-N
• SMILES: CC(=O)N(CC(C)C(=O)O)c1c(I)cc(I)c(N)c1I
• 蒸汽压: 3.21E-18mmHg at 25°C
• 折射率: 1.75
• 计算化学:

  1.疏水参数计算参考值（XlogP）:2.6

  2.氢键供体数量:2

  3.氢键受体数量:4

  4.可旋转化学键数量:4

  5.互变异构体数量:无

  6.拓扑分子极性表面积:83.6

  7.重原子数量:20

  8.表面电荷:0

  9.复杂度:383

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:1

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

碘西他酸毒性和生态

碘西他酸安全信息

• 海关编码: 2924299090

碘西他酸海关

• 海关编码: 2924299090
• 中文概述: 2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
• 申报要素: 品名, 成分含量, 用途, 包装
• Summary: 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

碘西他酸靶点实验

查看更多实验

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry 来源：NCGC 靶标：N/A External Id：TRND-SARS-CoV-2-cytotox-48hr

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry 来源：NCGC External Id：TRND-SARS-CoV-2-PP

实验名称：Dicer-mediated maturation of pre-microRNA 来源：Center for Chemical Genomics, University of Michigan 靶标：N/A External Id：TargetID_659_CEMA

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

共185条，当前第1页，共19页

1

2

3

4

5

碘西他酸英文别名

• Cholimil
• DRC 1201
• Acide iocetamique [INN-French]
• N-(3-amino-2,4,6-triiodophenyl)-3-acetamido-2-methyl-propionic acid
• Colebrina
• IOCETAMIC ACID
• Acidum jocetamicum
• Iocetamsaeure
• Acidum iocetamicum [INN-Latin]
• Cholebrine
• Acido iocetamico [INN-Spanish]