(1R)-9-[(3R,4R)-1,3-dimethylpiperidin-4-yl]-8-(2-fluoro-4-methoxyphenyl)-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one

• 常用名: (1R)-9-[(3R,4R)-1,3-dimethylpiperidin-4-yl]-8-(2-fluoro-4-methoxyphenyl)-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
• 英文名: (1R)-9-[(3R,4R)-1,3-dimethylpiperidin-4-yl]-8-(2-fluoro-4-methoxyphenyl)-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one
• CAS号: 1613718-79-8
• 分子量: 452.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₅H₂₉FN₄O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (1R)-9-[(3R,4R)-1,3-dimethylpiperidin-4-yl]-8-(2-fluoro-4-methoxyphenyl)-1-methyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one

物理化学性质

• 分子式: C₂₅H₂₉FN₄O₃
• 分子量: 452.5
• InChIKey: BYDKAYRDAFQMFD-ZMSDIMECSA-N
• SMILES: C[C@H]1CN(CC[C@H]1C2=CC3=C(C=C2C4=C(C=C(C=C4)OC)F)OCC5=NNC(=O)[C@H](N53)C)C

靶点实验

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实验名称：Reduction in concanavalin A-induced IL2 production in Balb/c mouse dosed orally 2 hrs... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3388409

实验名称：Inhibition of NK2 receptor (unknown origin) at 10 uM 来源：ChEMBL 靶标：Substance-K receptor External Id：CHEMBL3388408

实验名称：Drug level in concanavalin A-induced Balb/c mouse at 10 mg/kg, po dosed 2 hrs before ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3388411

实验名称：Unbound drug level in concanavalin A-induced Balb/c mouse at 10 mg/kg, po dosed 2 hrs... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3388410

实验名称：fCmax in mouse at 3 mg/kg, iv or 10 mg/kg, po 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3387805

实验名称：Unbound drug level in concanavalin A-induced Balb/c mouse at 10 mg/kg, po dosed 2 hrs... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3388412

实验名称：Half life in mouse at 3 mg/kg, iv or 10 mg/kg, po 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3387804

实验名称：Reduction in paw swelling in DBA/J mouse model of glucose 6-phosphate isomerase-induc... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3388415

实验名称：fAUC in mouse at 3 mg/kg, iv or 10 mg/kg, po 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3387806

实验名称：Toxicity in DBA/J mouse model of glucose 6-phosphate isomerase-induced athritis asses... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3388417

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