(2E)-3-[5-Methoxy-2-(trifluoromethyl)-1H-indol-3-yl]-1-(4-pyridinyl)-2-propen-1-one

• 常用名: (2E)-3-[5-Methoxy-2-(trifluoromethyl)-1H-indol-3-yl]-1-(4-pyridinyl)-2-propen-1-one
• 英文名: (2E)-3-[5-Methoxy-2-(trifluoromethyl)-1H-indol-3-yl]-1-(4-pyridinyl)-2-propen-1-one
• CAS号: 1620699-10-6
• 分子量: 346.3
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₁₃F₃N₂O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (2E)-3-[5-Methoxy-2-(trifluoromethyl)-1H-indol-3-yl]-1-(4-pyridinyl)-2-propen-1-one

物理化学性质

• 分子式: C₁₈H₁₃F₃N₂O₂
• 分子量: 346.3
• InChIKey: CWIHUVWNYHHZQG-HWKANZROSA-N
• SMILES: COc1ccc2[nH]c(C(F)(F)F)c(C=CC(=O)c3ccncc3)c2c1

靶点实验

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实验名称：Growth inhibition of human U251 cells after 24 hrs sulphorhodomine B colorimetric ass... 来源：ChEMBL 靶标：U-251 External Id：CHEMBL3424673

实验名称：Inhibition of tubulin polymerization in in human U251 cells at 0.1 uM after 4 hrs by ... 来源：ChEMBL 靶标：Tubulin alpha-3C chain External Id：CHEMBL3424732

实验名称：Growth inhibition of human U251 cells at 2.5 uM after 24 hrs sulphorhodomine B colori... 来源：ChEMBL 靶标：U-251 External Id：CHEMBL3424679

实验名称：Inhibition of tubulin polymerization in in human U251 cells at 3 uM after 4 hrs by im... 来源：ChEMBL 靶标：Tubulin alpha-3C chain External Id：CHEMBL3424731

实验名称：Induction of methuosis in human U251 cells assessed as small cytoplasmic vacuolizatio... 来源：ChEMBL 靶标：U-251 External Id：CHEMBL3424682

实验名称：Cytotoxicity against human U251 cells at 0.1 uM after 48 hrs by phase contrast micros... 来源：ChEMBL 靶标：U-251 External Id：CHEMBL3424683

实验名称：Induction of methuosis in human U251 cells assessed as rounded up and detached at 2.5... 来源：ChEMBL 靶标：U-251 External Id：CHEMBL3424680

实验名称：Induction of methuosis in human U251 cells assessed as rounded up and detached at 0.6... 来源：ChEMBL 靶标：U-251 External Id：CHEMBL3424681

实验名称：Cell cycle arrest in human U251 cells assessed as accumulation at G2/M phase at 3 uM ... 来源：ChEMBL 靶标：U-251 External Id：CHEMBL3424723

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