5-HT6R antagonist 2

更新时间：2026-03-11 11:26:28

5-HT6R antagonist 2用途

5-HT6R antagonist 2 (compound 29) 是一种 5-HT6 受体拮抗剂。

英文名	5-HT6R antagonist 2

描述	5-HT6R antagonist 2 (compound 29) 是一种 5-HT6 受体拮抗剂。
相关类别	研究领域 >> 其他信号通路 >> 其他 >> 其他
参考文献	[1]. Gałęzowski M,et al. 5-HT6 receptor antagonists. Design, synthesis, and structure-activity relationship of substituted 2-(1-methyl-4-piperazinyl)pyridines. Bioorg Med Chem Lett. 2023 Oct 6;96:129497 4.

分子式	C₂₃H₃₁N₃O₂
分子量	381.51

实验名称：AUClast in mouse plasma at 10 mg/kg, sc
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5391059

实验名称：Tmax in mouse plasma at 10 mg/kg, sc
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5391057

实验名称：Efflux ratio of permeability from apical to basolateral side over basolateral to apic...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5391051

实验名称：Permeability across apical to basolateral side in human Caco-2 cells
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5391050

实验名称：Permeability of the compound by PAMPA method
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5391049

实验名称：Thermodynamic solubility of compound at pH 7.4
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5391048

实验名称：Lipophilicity, logD of compound at pH 7.4
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5391047

实验名称：Metabolic stability in human hepatocyte assessed as intrinsic clearance
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5391046

实验名称：Metabolic stability in rat microsome assessed as intrinsic clearance
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5391045

实验名称：Metabolic stability in mouse microsome assessed as intrinsic clearance
来源：ChEMBL
靶标：N/A
External Id：CHEMBL5391044

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