2-Methyl-N-[cis-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclobutyl]-1-propanesulfonamide

• 常用名: 2-Methyl-N-[cis-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclobutyl]-1-propanesulfonamide
• 英文名: 2-Methyl-N-[cis-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclobutyl]-1-propanesulfonamide
• CAS号: 1622902-69-5
• 分子量: 337.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₅H₂₃N₅O₂S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-Methyl-N-[cis-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclobutyl]-1-propanesulfonamide

物理化学性质

• 分子式: C₁₅H₂₃N₅O₂S
• 分子量: 337.4
• InChIKey: MWVPRKLUXDJOMU-UHFFFAOYSA-N
• SMILES: CC(C)CS(=O)(=O)NC1CC(C1)N(C)C2=NC=NC3=C2C=CN3

靶点实验

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实验名称：Inhibition of recombinant human JAK3 using FITC-KGGEEEEYFELVKK as substrate in presen... 来源：ChEMBL 靶标：Tyrosine-protein kinase JAK3 External Id：CHEMBL4022976

实验名称：Inhibition of recombinant human TYK2 using 5'FAM-KKSRGDYMTMQID as substrate in presen... 来源：ChEMBL 靶标：Non-receptor tyrosine-protein kinase TYK2 External Id：CHEMBL4022977

实验名称：Apparent intrinsic clearance in human liver microsomes at 1 uM 来源：ChEMBL 靶标：Liver External Id：CHEMBL4022974

实验名称：Octanol/water phosphate buffer partition coefficient, log D of compound at pH 7.4 来源：ChEMBL 靶标：N/A External Id：CHEMBL4022975

实验名称：Inhibition of JAK1/TYK2 in human whole blood assessed as reduction in IFNalpha induce... 来源：ChEMBL 靶标：Tyrosine-protein kinase JAK1 External Id：CHEMBL4022972

实验名称：Inhibition of JAK2 in CD34+ human whole blood assessed as reduction in EOP induced ST... 来源：ChEMBL 靶标：Tyrosine-protein kinase JAK2 External Id：CHEMBL4022973

实验名称：Inhibition of recombinant human JAK2 using FITC-KGGEEEEYFELVKK as substrate in presen... 来源：ChEMBL 靶标：Tyrosine-protein kinase JAK2 External Id：CHEMBL4022970

实验名称：Selectivity ratio of IC50 for recombinant human JAK2 to IC50 for recombinant human JA... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4022971

实验名称：Inhibition of recombinant human JAK1 using 5'FAM-KKSRGDYMTMQID as substrate in presen... 来源：ChEMBL 靶标：Tyrosine-protein kinase JAK1 External Id：CHEMBL4022969

实验名称：Caliper Enzyme Assay from US Patent US10966980: "Pyrrolo[2,3-d]pyrimidine derivatives... 来源：BindingDB 靶标：N/A External Id：BindingDB_9802_1

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