1-乙酰基-4-(4-硝基苯基)哌嗪结构式
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常用名 | 1-乙酰基-4-(4-硝基苯基)哌嗪 | 英文名 | 9,10-DIHYDRO-4H-BENZO(4,5)CYCLOHEPTA(1,2-B)THIOPHEN-4-ONE |
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| CAS号 | 16264-08-7 | 分子量 | 249.26600 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C12H15N3O3 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | N/A |
| 中文名 | 1-乙酰基-4-(4-硝基苯基)哌嗪 |
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| 英文名 | 1-[4-(4-nitrophenyl)piperazin-1-yl]ethanone |
| 英文别名 | 更多 |
| 分子式 | C12H15N3O3 |
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| 分子量 | 249.26600 |
| 精确质量 | 249.11100 |
| PSA | 69.37000 |
| LogP | 1.78940 |
| InChIKey | QUZMCJMGHMRZHA-UHFFFAOYSA-N |
| SMILES | CC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1 |
| 储存条件 | 室温 |
| 海关编码 | 2933599090 |
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~91%
1-乙酰基-4-(4-硝基苯基)哌嗪 16264-08-7 |
| 文献:SANOFI Patent: US2012/277220 A1, 2012 ; Location in patent: Page/Page column 18-19 ; |
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~89%
1-乙酰基-4-(4-硝基苯基)哌嗪 16264-08-7 |
| 文献:Katz, H. E.; Schilling, M. L. Journal of the American Chemical Society, 1989 , vol. 111, # 19 p. 7554 - 7557 |
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~72%
1-乙酰基-4-(4-硝基苯基)哌嗪 16264-08-7 |
| 文献:Chen, Li; Ding, Qingjie; Gillespie, Paul; Kim, Kyungjin; Lovey, Allen John; McComas, Warren William; Mullin JR., John Guilfoye; Perrotta, Agostino Patent: US2002/151554 A1, 2002 ; |
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1-乙酰基-4-(4-硝基苯基)哌嗪 16264-08-7 |
| 文献:CYCLACEL LIMITED Patent: WO2004/43953 A1, 2004 ; Location in patent: Page 52 ; WO 2004/043953 A1 |
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1-乙酰基-4-(4-硝基苯基)哌嗪 16264-08-7 |
| 文献:Nguyen, Thuy; Sakasegawa, Yuji; Doh-Ura, Katsumi; Go, Mei-Lin European Journal of Medicinal Chemistry, 2011 , vol. 46, # 7 p. 2917 - 2929 |
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~%
1-乙酰基-4-(4-硝基苯基)哌嗪 16264-08-7 |
| 文献:Chapdelaine, Marc; Davenport, Timothy; Haeberlein, Markus; Horchler, Carey; McCauley, John; Pierson, Edward; Sohn, Daniel Patent: US2004/87575 A1, 2004 ; US 20040087575 A1 |
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~99%
1-乙酰基-4-(4-硝基苯基)哌嗪 16264-08-7 |
| 文献:Booth, Richard John; Dobrusin, Ellen Myra; Josyula, Vara Prasad Venkata Nagendra; McNamara, Dennis Joseph; Toogood, Peter Laurence Patent: US2003/73668 A1, 2003 ; US 20030073668 A1 |
| 1-乙酰基-4-(4-硝基苯基)哌嗪上游产品 7 | |
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| 1-乙酰基-4-(4-硝基苯基)哌嗪下游产品 1 | |
| 海关编码 | 2933599090 |
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| 中文概述 | 2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期 |
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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实验名称:Primary cell-based high-throughput screening assay for identification of compounds th...
来源:Johns Hopkins Ion Channel Center
靶标:regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id:JHICC_RGS_Act_HTS
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实验名称:Luminescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id:OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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实验名称:QFRET-based biochemical primary high throughput screening assay to identify exosite i...
来源:The Scripps Research Institute Molecular Screening Center
靶标:disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id:ADAM17_INH_QFRET_1536_1X%INH PRUN
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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实验名称:uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
来源:Burnham Center for Chemical Genomics
靶标:N/A
External Id:BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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实验名称:High throughput fluorescence intensity-based biochemical assay to screen for small mo...
来源:University of Pittsburgh Molecular Library Screening Center
靶标:furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id:MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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实验名称:Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
来源:Broad Institute
靶标:FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id:2147-01_Inhibitor_SinglePoint_HTS_Activity
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify pos...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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实验名称:Fluorescence polarization-based biochemical high throughput primary assay to identify...
来源:The Scripps Research Institute Molecular Screening Center
靶标:RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id:SIAE_INH_FP_1536_1X%INH PRUN
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| 4-(4-nitrophenyl)-1-acetylpiperazine |
| 1-(4-(4-nitrophenyl)piperazin-1-yl)ethanone |
| 1-acetyl-4-(4-nitrophenyl)-piperazine |
| 1-[4-(4-Nitrophenyl)piperazin-1-yl]ethan-1-one |
| 4-(4-Acetylpiperazinyl)-1-nitrobenzene |
| 1-[4-(4-Nitro-phenyl)-piperazinyl]-ethanone |