(E)-1-(3-(3,4,5-Trimethoxyphenyl)acryloyl)-1H-pyrrol-2(5H)-one

• 常用名: (E)-1-(3-(3,4,5-Trimethoxyphenyl)acryloyl)-1H-pyrrol-2(5H)-one
• 英文名: (E)-1-(3-(3,4,5-Trimethoxyphenyl)acryloyl)-1H-pyrrol-2(5H)-one
• CAS号: 1638366-87-6
• 分子量: 303.31
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₆H₁₇NO₅
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (E)-1-(3-(3,4,5-Trimethoxyphenyl)acryloyl)-1H-pyrrol-2(5H)-one

物理化学性质

• 分子式: C₁₆H₁₇NO₅
• 分子量: 303.31
• InChIKey: RZTXFCPQEOFMDN-VOTSOKGWSA-N
• SMILES: COc1cc(C=CC(=O)N2CC=CC2=O)cc(OC)c1OC

靶点实验

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实验名称：Induction of senescence in human WI-38 cells 来源：ChEMBL 靶标：WI-38 External Id：CHEMBL5346227

实验名称：Antiproliferative activity against human WI-38 cells 来源：ChEMBL 靶标：WI-38 External Id：CHEMBL5346226

实验名称：Induction of ROS production in ionizing radiation induced human WI38 senescent cells ... 来源：ChEMBL 靶标：WI-38 External Id：CHEMBL4233058

实验名称：Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induc... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL3378219

实验名称：Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induc... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL3378218

实验名称：Senolytic activity against ionizing radiation induced human WI38 senescent cells asse... 来源：ChEMBL 靶标：WI-38 External Id：CHEMBL4233055

实验名称：Cytotoxicity against mouse RAW264.7 cells assessed as cell proliferation at 10 uM 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL3378221

实验名称：Senolytic activity against non-senescent human WI38 cells assessed as reduction in ce... 来源：ChEMBL 靶标：WI-38 External Id：CHEMBL4233054

实验名称：Cytotoxicity against mouse RAW264.7 cells assessed as cell proliferation at 1 uM 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL3378220

实验名称：Selectivity index, ratio of EC50 for non-senescent human WI38 cells to EC50 for ioniz... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4233056

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