(6R)-5-(6-chloro-1H-pyrrolo[2,3-b]pyridin-4-yl)-6-methyl-3-(1-methylsulfonylpiperidin-4-yl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine

• 常用名: (6R)-5-(6-chloro-1H-pyrrolo[2,3-b]pyridin-4-yl)-6-methyl-3-(1-methylsulfonylpiperidin-4-yl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine
• 英文名: (6R)-5-(6-chloro-1H-pyrrolo[2,3-b]pyridin-4-yl)-6-methyl-3-(1-methylsulfonylpiperidin-4-yl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine
• CAS号: 1639880-82-2
• 分子量: 449.0
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₂₅ClN₆O₂S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (6R)-5-(6-chloro-1H-pyrrolo[2,3-b]pyridin-4-yl)-6-methyl-3-(1-methylsulfonylpiperidin-4-yl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine

物理化学性质

• 分子式: C₂₀H₂₅ClN₆O₂S
• 分子量: 449.0
• InChIKey: WJVYZVMUDBIEES-CYBMUJFWSA-N
• SMILES: CC1Cn2ncc(C3CCN(S(C)(=O)=O)CC3)c2CN1c1cc(Cl)nc2[nH]ccc12

靶点实验

查看更多实验

实验名称：Oral bioavailability in rat at 2.5 mg/kg 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3372393

实验名称：Inhibition of ATR (unknown origin) using Avi-tagged protein substrate by alphascreen ... 来源：ChEMBL 靶标：Serine/threonine-protein kinase ATR External Id：CHEMBL3379628

实验名称：Octanol-water distribution coefficient, log D of the compound with pH 7.4 PBS buffer 来源：ChEMBL 靶标：N/A External Id：CHEMBL3379635

实验名称：Apparent permeability across basolateral to apical side in human Caco2 cells at pH 7.... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3379637

实验名称：Apparent permeability across apical to basolateral side in human Caco2 cells at pH 7.... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3379636

实验名称：Clearance in rat at 2.5 mg/kg 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3379639

实验名称：Half life in rat at 2.5 mg/kg 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3379641

实验名称：Volume of distribution at steady state in rat at 2.5 mg/kg 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3379640

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