Adenosine, 2-methyl

更新时间：2025-09-21 18:55:20

Adenosine, 2-methyl结构式	常用名	Adenosine, 2-methyl	英文名	Adenosine, 2-methyl
	CAS号	16526-56-0	分子量	281.27
	密度	1.96g/cm3	沸点	517.8ºC at 760mmHg
	分子式	C₁₁H₁₅N₅O₄	熔点	N/A
	MSDS	N/A	闪点	266.9ºC

Adenosine, 2-methyl用途

2-甲基腺苷是一种腺苷类似物。腺苷类似物主要起到平滑肌血管扩张剂的作用,也被证明可以抑制癌症的进展。该系列中流行的产品有磷酸腺苷、阿卡地辛(HY-13417)、氯法拉滨(HY-A0005)、磷酸氟达拉滨(HY-B0028)和维达拉宾(HY-B0277)[1]。

英文名	2-methyladenosine
英文别名	更多

描述	2-甲基腺苷是一种腺苷类似物。腺苷类似物主要起到平滑肌血管扩张剂的作用,也被证明可以抑制癌症的进展。该系列中流行的产品有磷酸腺苷、阿卡地辛(HY-13417)、氯法拉滨(HY-A0005)、磷酸氟达拉滨(HY-B0028)和维达拉宾(HY-B0277)[1]。
相关类别	信号通路 >> 细胞周期/DNA损伤 >> 核苷抗代谢药/类似物研究领域 >> 其他
参考文献	[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

密度	1.96g/cm3
沸点	517.8ºC at 760mmHg
分子式	C₁₁H₁₅N₅O₄
分子量	281.27
闪点	266.9ºC
精确质量	281.11200
PSA	139.54000
InChIKey	IQZWKGWOBPJWMX-IOSLPCCCSA-N
SMILES	Cc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1
蒸汽压	1.51E-11mmHg at 25°C
折射率	1.856

三甲基铝

75-24-1

2-碘腺苷

35109-88-7

Adenosine, 2-methyl

16526-56-0

文献：GENZYME CORPORATION Patent: WO2008/157438 A1, 2008 ; Location in patent: Page/Page column 29-30 ;

1H-Imidazole-4-...

23192-64-5

~37%

Adenosine, 2-methyl

16526-56-0

文献：Nippon Zoki Pharmaceutical Co., Ltd. Patent: US4843066 A1, 1989 ;

未登录

53293-86-0

Adenosine, 2-methyl

16526-56-0

文献：Hirth, Bradford; Barker Jr., Robert H.; Celatka, Cassandra A.; Klinger, Jeffrey D.; Liu, Hanlan; Nare, Bakela; Nijjar, Amarjit; Phillips, Margaret A.; Sybertz, Edmund; Willert, Erin K.; Xiang, Yibin Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 11 p. 2916 - 2919

乙酸酐

108-24-7

2-甲基-1H-嘌呤-6-胺

1445-08-5

Adenosine, 2-methyl

16526-56-0

文献：Davoll; Lowy Journal of the American Chemical Society, 1952 , vol. 74, p. 1563,1565

过氧化乙酸叔丁酯

107-71-1

腺苷

58-61-7

8-methyladenosine

56973-12-7

Adenosine, 2-methyl

16526-56-0

详细

文献：Zady, Mona F.; Wong, John L. Journal of Organic Chemistry, 1980 , vol. 45, # 12 p. 2373 - 2377

Adenosine, 2-methyl上游产品 7
CAS号75-24-1 三甲基铝 CAS号35109-88-7 2-碘腺苷 CAS号23192-64-5 1H-Imidazole-4-... CAS号108-24-7 乙酸酐
CAS号1445-08-5 2-甲基-1H-嘌呤-6-胺 CAS号107-71-1 过氧化乙酸叔丁酯 CAS号58-61-7 腺苷
Adenosine, 2-methyl下游产品 0

实验名称：Minimum inhibitory concentration against Mycobacterium tuberculosis
来源：ChEMBL
靶标：Mycobacterium tuberculosis
External Id：CHEMBL830563

实验名称：Selectivity index, ratio of IC50 for african green monkey Vero cells to MIC for Mycob...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL2353304

实验名称：Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehy...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL684057

实验名称：Cytotoxicity against african green monkey Vero cells by non-radioactive cell prolifer...
来源：ChEMBL
靶标：Vero
External Id：CHEMBL2353319

实验名称：Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assess...
来源：ChEMBL
靶标：Mycobacterium tuberculosis
External Id：CHEMBL2350721

实验名称：Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assess...
来源：ChEMBL
靶标：Mycobacterium tuberculosis
External Id：CHEMBL2350719

实验名称：Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehy...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL684048

实验名称：Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehy...
来源：ChEMBL
靶标：Glyceraldehyde-3-phosphate dehydrogenase
External Id：CHEMBL684096

共8条，当前第1页，共1页

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