4-Pyrimidinamine, 6-(1H-indol-3-yl)-N-[4-(4-methyl-1-piperazinyl)phenyl]

• 常用名: 4-Pyrimidinamine, 6-(1H-indol-3-yl)-N-[4-(4-methyl-1-piperazinyl)phenyl]
• 英文名: 4-Pyrimidinamine, 6-(1H-indol-3-yl)-N-[4-(4-methyl-1-piperazinyl)phenyl]
• CAS号: 1679330-19-8
• 分子量: 384.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₄N₆
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 4-Pyrimidinamine, 6-(1H-indol-3-yl)-N-[4-(4-methyl-1-piperazinyl)phenyl]

物理化学性质

• 分子式: C₂₃H₂₄N₆
• 分子量: 384.5
• InChIKey: BMFODXAZKLMRNP-UHFFFAOYSA-N
• SMILES: CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=NC(=C3)C4=CNC5=CC=CC=C54

靶点实验

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实验名称：Inhibition of human recombinant N-terminal His6-tagged IGF-1R using fluorescence subs... 来源：ChEMBL 靶标：Insulin-like growth factor 1 receptor External Id：CHEMBL3424980

实验名称：Inhibition of human recombinant full length C-terminal His6-tagged CDK2 expressed in ... 来源：ChEMBL 靶标：Cyclin-dependent kinase 2 External Id：CHEMBL3424981

实验名称：Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-... 来源：ChEMBL 靶标：Dual specificity tyrosine-phosphorylation-regulated kinase 1B External Id：CHEMBL3424978

实验名称：Inhibition of human full length C-terminal c-Myc tagged Dyrk1B phosphorylation overex... 来源：ChEMBL 靶标：Dual specificity tyrosine-phosphorylation-regulated kinase 1B External Id：CHEMBL3424979

实验名称：Clearance in Wistar Han rat blood at 2 umol/kg 来源：ChEMBL 靶标：Blood External Id：CHEMBL3424984

实验名称：Oral bioavailability in Wistar Han rat at 3 umol/kg 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3424985

实验名称：Intrinsic clearance in Wistar Han rat hepatocytes assessed per 10'6 cells 来源：ChEMBL 靶标：Hepatocyte External Id：CHEMBL3424982

实验名称：Selectivity ratio of IC50 for human recombinant N-terminal His6-tagged IGF-1R to IC50... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3424989

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