N-[3-[2-(二甲基氨基)乙氧基]-4-甲氧基苯基]-2'-甲基-4'-(5-甲基-1,2,4-恶二唑-3-基)-[1,1'-联苯]-4-甲酰胺

• 常用名: N-[3-[2-(二甲基氨基)乙氧基]-4-甲氧基苯基]-2'-甲基-4'-(5-甲基-1,2,4-恶二唑-3-基)-[1,1'-联苯]-4-甲酰胺
• 英文名: SB-216641
• CAS号: 170230-39-4
• 分子量: 486.562
• 密度: 1.2±0.1 g/cm3
• 沸点: N/A
• 分子式: C₂₈H₃₁ClN₄O₄
• 熔点: N/A
• 闪点: N/A

名称

• 中文名: N-[3-[2-(二甲基氨基)乙氧基]-4-甲氧基苯基]-2'-甲基-4'-(5-甲基-1,2,4-恶二唑-3-基)-[1,1'-联苯]-4-甲酰胺
• 英文名: N-[3-[2-(dimethylamino)ethoxy]-4-methoxyphenyl]-4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzamide

物理化学性质

• 密度: 1.2±0.1 g/cm3
• 分子式: C₂₈H₃₁ClN₄O₄
• 分子量: 486.562
• 精确质量: 486.226715
• PSA: 89.72000
• LogP: 4.55
• InChIKey: JRNUKVFYILMMLX-UHFFFAOYSA-N
• SMILES: COc1ccc(NC(=O)c2ccc(-c3ccc(-c4noc(C)n4)cc3C)cc2)cc1OCCN(C)C
• 折射率: 1.602

靶点实验

查看更多实验

实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：Effect of compound on [35S]GTP-gamma-S, radioligand binding CHO cells expressing huma... 来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1B External Id：CHEMBL616462

实验名称：GTPgammaS radioligand binding assay 来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1B External Id：CHEMBL616955

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1100

实验名称：qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primar... 来源：NCGC 靶标：67.9K protein [Vaccinia virus] External Id：Vaccinia-p2mCherry

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1101

实验名称：Human 5-HT1B receptor (5-Hydroxytryptamine receptors) 来源：IUPHAR-DB 靶标：5-HT1B receptor (5-Hydroxytryptamine receptors) [Homo sapiens] External Id：2_Human

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary ... 来源：NCGC 靶标：67.9K protein [Vaccinia virus] External Id：Vaccinia-p2Venus

实验名称：qHTS for inhibitors of Vif-A3G interactions: Validation 来源：NCGC 靶标：DNA dC->dU-editing enzyme APOBEC-3G [Homo sapiens] External Id：VIFG001

共30条，当前第1页，共3页

1

2

3

英文别名

• Tocris-1242
• N-{3-[2-(Dimethylamino)ethoxy]-4-methoxyphenyl}-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxamide
• N-{3-[2-(Dimethylamino)ethoxy]-4-methoxyphenyl}-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-4-biphenylcarboxamide
• SB-216641