5-[(5R)-5-amino-3,3-difluoropiperidin-1-yl]-N-[3-(difluoromethyl)-1-methyl-1H-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

• 常用名: 5-[(5R)-5-amino-3,3-difluoropiperidin-1-yl]-N-[3-(difluoromethyl)-1-methyl-1H-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
• 英文名: 5-[(5R)-5-amino-3,3-difluoropiperidin-1-yl]-N-[3-(difluoromethyl)-1-methyl-1H-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
• CAS号: 1710554-33-8
• 分子量: 426.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₁₈F₄N₈O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 5-[(5R)-5-amino-3,3-difluoropiperidin-1-yl]-N-[3-(difluoromethyl)-1-methyl-1H-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

物理化学性质

• 分子式: C₁₇H₁₈F₄N₈O
• 分子量: 426.4
• InChIKey: FMCYOILPKLBTED-SECBINFHSA-N
• SMILES: CN1C=C(C(=N1)C(F)F)NC(=O)C2=C3N=C(C=CN3N=C2)N4C[C@@H](CC(C4)(F)F)N

靶点实验

查看更多实验

实验名称：Oral bioavailability in rat at 1 mg/kg 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3592275

实验名称：Plasma clearance in rat at 0.5 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3592274

实验名称：Passive permeability in pig LLC-PK1 cells 来源：ChEMBL 靶标：LLC-PK1 External Id：CHEMBL3592271

实验名称：IRAK4 Kinase Assay from US Patent US10329294: "Pyrazolopyrimidine inhibitors of IRAK4... 来源：BindingDB 靶标：N/A External Id：BindingDB_3516_1

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