1,2-双(甲磺酰基)-1-(2-氯乙基)-2-(甲氨羰基)肼

• 常用名: 1,2-双(甲磺酰基)-1-(2-氯乙基)-2-(甲氨羰基)肼
• 英文名: 1-[2-chloroethyl(methylsulfonyl)amino]-3-methyl-1-methylsulfonylurea
• CAS号: 173424-77-6
• 分子量: 307.77500
• 密度: 1.527g/cm3
• 沸点: N/A
• 分子式: C₆H₁₄ClN₃O₅S₂
• 熔点: N/A
• 闪点: N/A

名称

• 中文名: 1,2-双(甲磺酰基)-1-(2-氯乙基)-2-(甲氨羰基)肼
• 英文名: 1-[2-chloroethyl(methylsulfonyl)amino]-3-methyl-1-methylsulfonylurea

物理化学性质

• 密度: 1.527g/cm3
• 分子式: C₆H₁₄ClN₃O₅S₂
• 分子量: 307.77500
• 精确质量: 307.00600
• PSA: 120.62000
• LogP: 1.55530
• InChIKey: PVCULFYROUOVGJ-UHFFFAOYSA-N
• SMILES: CNC(=O)N(N(CCCl)S(C)(=O)=O)S(C)(=O)=O
• 折射率: 1.546

靶点实验

查看更多实验

实验名称：Average survival time of treated /control mice*100 was determined at a daily dose of ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL723554

实验名称：%60 day survivors were determined for the compound as the mouse surviving after the 6... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL727635

实验名称：Average percent change in body weight from onset to termination of therapy at dose 10... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL717978

实验名称：Average percent change in body weight from onset to termination of therapy at dose 15... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL717980

实验名称：Average percent change in body weight from onset to termination of therapy at dose 5(... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL717984

实验名称：Cytotoxicity against human DU145 cells expressing AGT after 4 to 24 hrs by clonogenic... 来源：ChEMBL 靶标：DU-145 External Id：CHEMBL2339116

实验名称：%60 day survivors were determined for the compound as the mouse surviving after the 6... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL727629

实验名称：Cytotoxicity against human DU145 cells expressing AGT at 10 to 80 uM after 4 hrs by c... 来源：ChEMBL 靶标：DU-145 External Id：CHEMBL2339120

实验名称：Binding affinity to mouse L1210 cell DNA assessed as DNA cross-linking activity at 10... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2339119

实验名称：%60 day survivors were determined for the compound as the mouse surviving after the 6... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL727631

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英文别名

• Cloretazine
• 1,2-bis(methylsulfonyl)-1-(2-chlorchloroethyl)-2--2-(methylaminocarbonyl)hydrazine
• Onrigin
• Laromustine (USAN)
• Laromustine
• 101M
• 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(methylamino)carbonyl]-hydrazine