6-[[3-(Dimethylamino)propyl]amino]-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one

• 常用名: 6-[[3-(Dimethylamino)propyl]amino]-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one
• 英文名: 6-[[3-(Dimethylamino)propyl]amino]-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one
• CAS号: 174634-20-9
• 分子量: 347.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₂₁N₃O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 6-[[3-(Dimethylamino)propyl]amino]-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one

物理化学性质

• 分子式: C₂₁H₂₁N₃O₂
• 分子量: 347.4
• InChIKey: KLGVMWBWHQUYJL-UHFFFAOYSA-N
• SMILES: CN(C)CCCNc1nc2cc(O)ccc2c2c1C(=O)c1ccccc1-2

靶点实验

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实验名称：Binding affinity to calf thymus DNA by fluorescence titration 来源：ChEMBL 靶标：DNA External Id：CHEMBL964482

实验名称：Binding affinity to calf thymus DNA assessed as melting temperature at 1 uM by fluore... 来源：ChEMBL 靶标：DNA External Id：CHEMBL964480

实验名称：Inhibition of human topoisomerase 2 mediated pLAZ DNA relaxation by gel electrophores... 来源：ChEMBL 靶标：N/A External Id：CHEMBL954855

实验名称：Cytotoxicity measured using the H69 parental (H69/P) human small cell lung carcinoma ... 来源：ChEMBL 靶标：NCI-H69 External Id：CHEMBL683176

实验名称：Rf is the resistance factor and is the ratio of the IC50 on the resistant cell line o... 来源：ChEMBL 靶标：NCI-H69 External Id：CHEMBL639901

实验名称：Cytotoxicity measured using the drug resistant, P-glycoprotein (Pgp) expressing human... 来源：ChEMBL 靶标：NCI-H69 External Id：CHEMBL683165

实验名称：Cytotoxicity against mitoxantrone-resistant human HL60/MX2 cells after 72 hrs 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL964487

实验名称：Resistant index, ratio of IC50 for mitoxantrone-resistant human HL60/MX2 cells to IC5... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL965236

实验名称：Cytotoxicity against human mitoxantrone-sensitive HL60 cells after 72 hrs 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL964486

实验名称：Inhibition of human topoisomerase 1 mediated pLAZ DNA relaxation by gel electrophores... 来源：ChEMBL 靶标：N/A External Id：CHEMBL964484

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