6-[[2-methoxy-5-(trifluoromethyl)anilino]methyl]-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine

• 常用名: 6-[[2-methoxy-5-(trifluoromethyl)anilino]methyl]-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine
• 英文名: 6-[[2-methoxy-5-(trifluoromethyl)anilino]methyl]-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine
• CAS号: 174654-98-9
• 分子量: 378.35200
• 密度: N/A
• 沸点: 597.7ºC at 760 mmHg
• 分子式: C₁₇H₁₇F₃N₆O
• 熔点: N/A
• 闪点: 315.3ºC

名称

• 英文名: 6-[[2-methoxy-5-(trifluoromethyl)anilino]methyl]-5-methylpyrido[2,3-d]pyrimidine-2,4-diamine

物理化学性质

• 沸点: 597.7ºC at 760 mmHg
• 分子式: C₁₇H₁₇F₃N₆O
• 分子量: 378.35200
• 闪点: 315.3ºC
• 精确质量: 378.14200
• PSA: 113.43000
• LogP: 3.07030
• InChIKey: XNEOAXKYJADVSI-UHFFFAOYSA-N
• SMILES: COc1ccc(C(F)(F)F)cc1NCc1cnc2nc(N)nc(N)c2c1C
• 蒸汽压: 2.99E-14mmHg at 25°C
• 折射率: 1.666

靶点实验

查看更多实验

实验名称：Inhibitory activity against rat liver dihydrofolate reductase 来源：ChEMBL 靶标：Dihydrofolate reductase External Id：CHEMBL665442

实验名称：Antimycobacterial activity against Mycobacterium avium complex dihydrofolate reductas... 来源：ChEMBL 靶标：Dihydrofolate reductase External Id：CHEMBL665360

实验名称：Antimycobacterial activity scale was evaluated and found to be highly active against ... 来源：ChEMBL 靶标：Dihydrofolate reductase External Id：CHEMBL667000

实验名称：Inhibition of Toxoplasma gondii cell growth 来源：ChEMBL 靶标：Toxoplasma gondii External Id：CHEMBL813899

实验名称：Inhibitory activity against Pneumocystis carinii dihydrofolate reductase 来源：ChEMBL 靶标：Dihydrofolate reductase External Id：CHEMBL664188

实验名称：Ratio of IC50 rat liver DHFR vs IC50 of Toxoplasma gondii DHFR 来源：ChEMBL 靶标：Dihydrofolate reductase; T. gondii vs rat External Id：CHEMBL848792

实验名称：Ratio of IC50 rat liver DHFR vs IC50 of Pneumocystis carinii DHFR 来源：ChEMBL 靶标：Dihydrofolate reductase; P. carinii vs rat External Id：CHEMBL848791

实验名称：Antimycobacterial activity scale found to be highly active against human dihydrofolat... 来源：ChEMBL 靶标：Dihydrofolate reductase External Id：CHEMBL667182

实验名称：Inhibitory activity against Toxoplasma gondii dihydrofolate reductase 来源：ChEMBL 靶标：Bifunctional dihydrofolate reductase-thymidylate synthase External Id：CHEMBL665590

实验名称：Antimycobacterial activity against human dihydrofolate reductase (hDHFR) 来源：ChEMBL 靶标：Dihydrofolate reductase External Id：CHEMBL669986

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