1h-Imidazole,2-(3-fluoro-4-methoxyphenyl)-1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)

• 常用名: 1h-Imidazole,2-(3-fluoro-4-methoxyphenyl)-1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)
• 英文名: 1h-Imidazole,2-(3-fluoro-4-methoxyphenyl)-1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)
• CAS号: 177660-67-2
• 分子量: 414.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₁₄F₄N₂O₃S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 1h-Imidazole,2-(3-fluoro-4-methoxyphenyl)-1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)

物理化学性质

• 分子式: C₁₈H₁₄F₄N₂O₃S
• 分子量: 414.4
• InChIKey: UFSJAWLGOHKVBH-UHFFFAOYSA-N
• SMILES: COc1ccc(-c2nc(C(F)(F)F)cn2-c2ccc(S(C)(=O)=O)cc2)cc1F

靶点实验

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实验名称：Inhibitory activity in the adjuvant induced arthritis model of chronic inflammation i... 来源：ChEMBL 靶标：Prostaglandin G/H synthase 1 External Id：CHEMBL780466

实验名称：Inhibitory activity against prostaglandin G/H synthase 2 (COX-2) 来源：ChEMBL 靶标：Prostaglandin G/H synthase 2 External Id：CHEMBL858334

实验名称：Inhibition of human Prostaglandin G/H synthase 2 来源：ChEMBL 靶标：Prostaglandin G/H synthase 2 External Id：CHEMBL763870

实验名称：Effective dose was evaluated in the carrageenan induced model of hyperalgesia in the ... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL780467

实验名称：Concentration required to inhibit human Prostaglandin G/H synthase 2 (COX-2) by 50% 来源：ChEMBL 靶标：Prostaglandin G/H synthase 2 External Id：CHEMBL762906

实验名称：Gastric lesions in the mouse after intragastric administration of 200 mpk number of m... 来源：ChEMBL 靶标：N/A External Id：CHEMBL811503

实验名称：Gastric lesions in the mouse after intragastric administration of 20 mpk number of mo... 来源：ChEMBL 靶标：N/A External Id：CHEMBL814369

实验名称：IC50 ratio measured as the IC50 of COX-1 to that of COX-2 来源：ChEMBL 靶标：Prostaglandin G/H synthase 1 External Id：CHEMBL849096

实验名称：Effective dose was evaluated in the carrageenan induced model of paw edema in the rat 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL780471

实验名称：Concentration required to inhibit human prostaglandin G/H synthase 1 (COX-1) by 50% 来源：ChEMBL 靶标：Prostaglandin G/H synthase 1 External Id：CHEMBL768737

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