US10093646, Example 8

• 常用名: US10093646, Example 8
• 英文名: US10093646, Example 8
• CAS号: 1801747-12-5
• 分子量: 366.3
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₂₁Cl₂N₅
• 熔点: N/A
• 闪点: N/A

US10093646, Example 8名称

• 英文名: US10093646, Example 8

US10093646, Example 8物理化学性质

• 分子式: C₁₇H₂₁Cl₂N₅
• 分子量: 366.3
• InChIKey: ZAMNYDQBNJFTSZ-UHFFFAOYSA-N
• SMILES: CC1(CN)CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1

US10093646, Example 8靶点实验

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实验名称：SHP2 Allosteric Inhibition Assay from US Patent US12053470: "Pharmaceutical combinati... 来源：BindingDB 靶标：N/A External Id：BindingDB_12240_1

实验名称：Inhibition of human ERG by Q-patch assay 来源：ChEMBL 靶标：Potassium voltage-gated channel subfamily H member 2 External Id：CHEMBL4701902

实验名称：Allosteric inhibition of 6x-histidine tagged human SHP2 (Met1-L525 residues) expresse... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 11 External Id：CHEMBL4701889

实验名称：Antiproliferative activity against human KYSE-520 cells 来源：ChEMBL 靶标：KYSE-520 cell line External Id：CHEMBL4701888

实验名称：Allosteric inhibition of human SHP2 in human KYSE-520 cells assessed as reduction in ... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 11 External Id：CHEMBL4701891

实验名称：SHP2 Allosteric Inhibition Assay from US Patent US11401259: "1-Pyridazin-/triazin-3-y... 来源：BindingDB 靶标：N/A External Id：BindingDB_10726_1

实验名称：Aqueous solubility of the compound at pH 6.8 来源：ChEMBL 靶标：N/A External Id：CHEMBL4701899

实验名称：SHP2 Allosteric Inhibition Assay from US Patent US10093646: "1-pyridazin-/triazin-3-y... 来源：BindingDB 靶标：N/A External Id：BindingDB_745_1

实验名称：Distribution coefficient, logD of the compound 来源：ChEMBL 靶标：N/A External Id：CHEMBL4701901

实验名称：Lipophilicity, logP of the compound 来源：ChEMBL 靶标：N/A External Id：CHEMBL4701900

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