RN-9893

• 常用名: RN-9893
• 英文名: RN-9893
• CAS号: 1803003-68-0
• 分子量: 500.491
• 密度: 1.4±0.1 g/cm3
• 沸点: N/A
• 分子式: C₂₁H₂₃F₃N₄O₅S
• 熔点: N/A
• 闪点: N/A

RN-9893用途

一种有效的,选择性口服生物可利用的TRPV4拮抗剂,小鼠,人和大鼠TRPV4通道的IC50分别为320,420和660 nM；TRPV4对TRPV1,TRPV3和TRPM8的选择性>15倍,其他54种常见的生物学目标。

RN-9893名称

• 英文名: RN-9893

RN-9893生物活性

• 描述: 一种有效的,选择性口服生物可利用的TRPV4拮抗剂,小鼠,人和大鼠TRPV4通道的IC50分别为320,420和660 nM；TRPV4对TRPV1,TRPV3和TRPM8的选择性>15倍,其他54种常见的生物学目标。
• 参考文献: References 1. Wei ZL, et al. Bioorg Med Chem Lett. 2015 Sep 15;25(18):4011-5. View Related Products by Target TRP Channel

RN-9893物理化学性质

• 密度: 1.4±0.1 g/cm3
• 分子式: C₂₁H₂₃F₃N₄O₅S
• 分子量: 500.491
• 精确质量: 500.134125
• LogP: 4.26
• 折射率: 1.584

RN-9893安全信息

• 危险品运输编码: NONH for all modes of transport

RN-9893靶点实验

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RN-9893英文别名

• N-{4-[(4-Isopropyl-1-piperazinyl)sulfonyl]phenyl}-2-nitro-4-(trifluoromethyl)benzamide
• MFCD29917838
• RN-9893
• N-(4-(4-Isopropylpiperazin-1-ylsulfonyl)phenyl)-2-nitro-4-(trifluoromethyl)benzamide