4-Fluoro-N-(1H-indol-5-yl)benzamide

• 常用名: 4-Fluoro-N-(1H-indol-5-yl)benzamide
• 英文名: 4-Fluoro-N-(1H-indol-5-yl)benzamide
• CAS号: 182564-41-6
• 分子量: 254.259
• 密度: 1.4±0.1 g/cm3
• 沸点: 374.9±22.0 °C at 760 mmHg
• 分子式: C₁₅H₁₁FN₂O
• 熔点: N/A
• 闪点: 180.5±22.3 °C

4-Fluoro-N-(1H-indol-5-yl)benzamide用途

Oct4诱导剂-1(化合物OAC-3)是一种有效的Oct4激活剂。Oct4诱导物-1激活Oct4和Nanog启动子,并增强诱导的多能干细胞(iPSC)的形成。Oct4诱导物-1通过提高效率和缩短重编程时间促进细胞的重编程[1]。

4-Fluoro-N-(1H-indol-5-yl)benzamide名称

• 英文名: oac3

4-Fluoro-N-(1H-indol-5-yl)benzamide生物活性

• 描述: Oct4诱导剂-1(化合物OAC-3)是一种有效的Oct4激活剂。Oct4诱导物-1激活Oct4和Nanog启动子,并增强诱导的多能干细胞(iPSC)的形成。Oct4诱导物-1通过提高效率和缩短重编程时间促进细胞的重编程[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 干细胞及 Wnt 通路 >> OCT3/4
• 体外研究: Oct4诱导物-1(化合物OAC-3；1μ。Oct4诱导物-1增加诱导多能干细胞(iPSC)的生成,并加速iPSC样集落的出现[1]。Oct4诱导物-1(1μM；4F(OSKM)感染的小鼠胚胎成纤维细胞(MEF))增强了iSF1培养基中的重编程效率[1]。
• 参考文献:

  [1]. Hong SY, et, al. Enhancers of induced pluripotent stem cell reprogramming. US20140154805.

4-Fluoro-N-(1H-indol-5-yl)benzamide物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 374.9±22.0 °C at 760 mmHg
• 分子式: C₁₅H₁₁FN₂O
• 分子量: 254.259
• 闪点: 180.5±22.3 °C
• 精确质量: 254.085541
• PSA: 44.89000
• LogP: 2.77
• InChIKey: RQJUZWRDCVBOMH-UHFFFAOYSA-N
• SMILES: O=C(Nc1ccc2[nH]ccc2c1)c1ccc(F)cc1
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.721
• 储存条件: -20°C，密闭，干燥

4-Fluoro-N-(1H-indol-5-yl)benzamide靶点实验

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4-Fluoro-N-(1H-indol-5-yl)benzamide英文别名

• 4-Fluoro-N-(1H-indol-5-yl)benzamide