Biotin-β-Amyloid (1-40)

• 常用名: Biotin-β-Amyloid (1-40)
• 英文名: Biotin-β-Amyloid (1-40)
• CAS号: 183906-14-1
• 分子量: 488.538
• 密度: 1.5±0.1 g/cm3
• 沸点: 748.0±60.0 °C at 760 mmHg
• 分子式: C₂₆H₂₈N₆O₄
• 熔点: N/A
• 闪点: 406.2±32.9 °C

Biotin-β-Amyloid (1-40)用途

Biotin-β-Amyloid (1-40) 是一种被 N 端标记的生物素化 Amyloid-ß-(1-40) 肽。

Biotin-β-Amyloid (1-40)名称

• 英文名: 7-{[(2-Phenylethyl){[1-(tetrahydro-2-furanylmethyl)-1H-tetrazol-5-yl]methyl}amino]methyl}[1,3]dioxolo[4,5-g]quinolin-6(5H)-one

Biotin-β-Amyloid (1-40)生物活性

• 描述: Biotin-β-Amyloid (1-40) 是一种被 N 端标记的生物素化 Amyloid-ß-(1-40) 肽。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
• 体外研究: β-淀粉样蛋白(1-40)是阿尔茨海默病患者大脑斑块中的一种主要蛋白质。它是老年斑块淀粉样蛋白的主要成分,是存在于大脑、脑脊液(CSF)和血浆中的生理肽[1]。生物素在生物技术工业中被广泛应用于结合蛋白质以进行生化分析。生物素可用于定性和定量检测、标记或固定化。
• 参考文献:

  [1]. Mikio Shoji, et al. Cerebrospinal fluid Abeta40 and Abeta42: natural course and clinical usefulness. Front Biosci. 2002 Apr 1;7:d997-1006.

Biotin-β-Amyloid (1-40)物理化学性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 748.0±60.0 °C at 760 mmHg
• 分子式: C₂₆H₂₈N₆O₄
• 分子量: 488.538
• 闪点: 406.2±32.9 °C
• 精确质量: 488.217194
• LogP: 3.40
• InChIKey: ZVJVNSZHSNKLLR-UHFFFAOYSA-N
• SMILES: O=c1[nH]c2cc3c(cc2cc1CN(CCc1ccccc1)Cc1nnnn1CC1CCCO1)OCO3
• 蒸汽压: 0.0±2.5 mmHg at 25°C
• 折射率: 1.715

Biotin-β-Amyloid (1-40)靶点实验

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实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

实验名称：Absorbance-based primary biochemical high throughput screening assay to identify acti... 来源：The Scripps Research Institute Molecular Screening Center 靶标：caspase-3 preproprotein [Homo sapiens] External Id：PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN

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Biotin-β-Amyloid (1-40)英文别名

• 7-{[(2-Phenylethyl){[1-(tetrahydro-2-furanylmethyl)-1H-tetrazol-5-yl]methyl}amino]methyl}[1,3]dioxolo[4,5-g]quinolin-6(5H)-one