MGAT2-IN-4

• 常用名: MGAT2-IN-4
• 英文名: MGAT2-IN-4
• CAS号: 1841424-92-7
• 分子量: 437.54
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₂₇N₅O
• 熔点: N/A
• 闪点: N/A

MGAT2-IN-4用途

MGAT2-IN-4(化合物33)是具有肝脏代谢稳定性的单酰基甘油转移酶2(MGAT2)的抑制剂。MGAT2-IN-4可用于肥胖、糖尿病和非酒精性脂肪性肝炎(NASH)的研究[1]。

MGAT2-IN-4名称

• 英文名: MGAT2-IN-4

MGAT2-IN-4生物活性

• 描述: MGAT2-IN-4(化合物33)是具有肝脏代谢稳定性的单酰基甘油转移酶2(MGAT2)的抑制剂。MGAT2-IN-4可用于肥胖、糖尿病和非酒精性脂肪性肝炎(NASH)的研究[1]。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 代谢疾病
• 靶点实验:

  Monoacylglycerol transferase 2 (MGAT2)[1]

• 参考文献:

  [1]. Moore F, et al. Discovery of novel pyridinones as MGAT2 inhibitors for the treatment of metabolic disorders. Bioorg Med Chem Lett. 2023 Jul 15;91:129362.

MGAT2-IN-4物理化学性质

• 分子式: C₂₇H₂₇N₅O
• 分子量: 437.54
• InChIKey: XMQKWTWPIMYWMG-UHFFFAOYSA-N
• SMILES: Cc1ccc(-c2cc(-c3ccc(C4=CCC(C)(C)CC4)cc3)[nH]c(=O)c2-c2nn[nH]n2)cc1

MGAT2-IN-4靶点实验

查看更多实验

实验名称：Metabolic stability in dog liver microsomes assessed as UDPGA mediated glucuronidatio... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5323321

实验名称：Metabolic stability in rat liver microsomes assessed as UDPGA mediated glucuronidatio... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5323322

实验名称：Metabolic stability in human liver microsomes assessed as UDPGA mediated glucuronidat... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5323320

实验名称：Inhibition of mouse MGAT2 by LC-MS analysis 来源：ChEMBL 靶标：2-acylglycerol O-acyltransferase 2 External Id：CHEMBL5323315

实验名称：Inhibition of human MGAT2 by LC-MS analysis 来源：ChEMBL 靶标：2-acylglycerol O-acyltransferase 2 External Id：CHEMBL5323325

实验名称：Metabolic stability in mouse liver microsomes assessed as UDPGA mediated glucuronidat... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5323323

实验名称：Metabolic stability in cynomolgus monkey liver microsomes assessed as UDPGA mediated ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5323324

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