(R)-4-(3-Ethylpiperazin-1-YL)-2-fluoro-N-(2-methylimidazo[1,2-A]pyrazin-6-YL)benzamide

• 常用名: (R)-4-(3-Ethylpiperazin-1-YL)-2-fluoro-N-(2-methylimidazo[1,2-A]pyrazin-6-YL)benzamide
• 英文名: (R)-4-(3-Ethylpiperazin-1-YL)-2-fluoro-N-(2-methylimidazo[1,2-A]pyrazin-6-YL)benzamide
• CAS号: 1845753-52-7
• 分子量: 382.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₂₃FN₆O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (R)-4-(3-Ethylpiperazin-1-YL)-2-fluoro-N-(2-methylimidazo[1,2-A]pyrazin-6-YL)benzamide

物理化学性质

• 分子式: C₂₀H₂₃FN₆O
• 分子量: 382.4
• InChIKey: FWJHZBXJJJTEFO-CQSZACIVSA-N
• SMILES: CCC1CN(c2ccc(C(=O)Nc3cn4cc(C)nc4cn3)c(F)c2)CCN1

靶点实验

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实验名称：Modulation of patient derived full length SMN2 pre mRNA splicing assessed as restorat... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4052097

实验名称：Induction of SMN protein levels in C/C-Allele SMA FVB mouse brain at 3 mg/kg, po qd f... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4052082

实验名称：Modulation of patient derived full length SMN2 pre mRNA splicing assessed as inclusio... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4052096

实验名称：Total AUC in wild type FVB mouse plasma at 10 mg/kg, po qd for 10 days by LC-MS/MS an... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4052080

实验名称：Induction of SMN protein levels in neonatal delta7 FVB mouse brain at 3 mg/kg, ip qd ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4052091

实验名称：Induction of SMN protein levels in neonatal delta7 FVB mouse brain at 0.3 mg/kg, ip q... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4052089

实验名称：Induction of SMN protein levels in neonatal delta7 FVB mouse brain at 1 mg/kg, ip qd ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4052090

实验名称：Total AUC in neonatal wild type FVB mouse plasma at 3 mg/kg, ip qd for 10 days by LC-... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4052087

实验名称：Induction of SMN protein levels in C/C-Allele SMA FVB mouse brain at 1 mg/kg, po qd f... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4052099

实验名称：Induction of SMN protein levels in C/C-Allele SMA FVB mouse brain at 10 mg/kg, po qd ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4052083

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